RANKL-RANK-OPG pathway in charcot diabetic foot: pathophysiology and clinical-therapeutic implications

T Greco, A Mascio, C Comisi, C Polichetti… - International Journal of …, 2023 - mdpi.com
Charcot Foot (CF), part of a broader condition known as Charcot Neuro-Osteoarthropathy
(CNO), is characterized by neuropathic arthropathy with a progressive alteration of the foot …

Targeting small GTPases and their prenylation in diabetes mellitus

E Gendaszewska-Darmach, MA Garstka… - Journal of medicinal …, 2021 - ACS Publications
A fundamental role of pancreatic β-cells to maintain proper blood glucose level is controlled
by the Ras superfamily of small GTPases that undergo post-translational modifications …

Conservative Management of Charcot Neuroarthropathy.

M Schweitzer, S Rockhill - Clinics in Podiatric Medicine and Surgery, 2022 - europepmc.org
Charcot can be a difficult clinical entity to diagnose in the acute phase, and clinicians should
have a high clinical suspicion in neuropathic patients who present with erythema, edema …

Prospective study of clinical, biochemical, and radiological characteristics of diabetic Charcot neuroarthropathy at a tertiary care centre

M Aruna, PR Kumar, DK Dash, D Patro… - International Journal of …, 2024 - Springer
Objective The aim of this study was to assess demographic, clinical, biochemical,
radiological profile and treatment response in diabetic patients with Charcot …

A Pilot Survey: Knowledge of Charcot Neuroarthropathy Among Family and Internal Medicine Practitioners

J Bilello, DC Jupiter - The Journal of Foot and Ankle Surgery, 2021 - Elsevier
Charcot neuroarthropathy secondary to diabetes mellitus is a serious complication, requiring
specialist management. As a relatively rare pathology bearing similarity to other, more …

[HTML][HTML] Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury

SI Stoica, I Tănase, V Ciobanu… - Journal of Medicine and …, 2019 - ncbi.nlm.nih.gov
We found differences related to the neuro-functional deficiency and clinical progress, among
non-consumers and chronic consumers of ethanol, with recent traumatic spinal cord injury …

Association between osteoprotegerin and charcot neuroarthropathy: a systematic review

R Ochoa-Précoma, BT Pacheco-Soto, LM Porchia… - Acta Diabetologica, 2021 - Springer
Aims Osteoprotegerin (OPG) has been associated with Charcot Neuroarthropathy (CN);
however, three studied OPG polymorphisms (1181C> G, 245A> C and 950 T> C) have …

[PDF][PDF] Distribution and analysis of Charcot foot in diabetes through Amit Jain's extended 'SCC'classification

AKC Jain, HC Apoorva, S Kumar, TR Hariprasad - Nat J Clin Orthop, 2019 - academia.edu
Objective: To analyze and distribute the Charcot foot in diabetes through the new Amit Jain's
classification for Charcot foot (E “SCC”) and to predict outcomes associated with this new …

Charcot Arthropathy of the Shoulder

S Metikala, DW Verheul, M Rajagopal, N Dixit… - Unusual Conditions That …, 2024 - Springer
Charcot arthropathy of the shoulder is a chronic progressive destructive process of the joint
and periarticular tissues. It is caused by loss of pain sensation in the joint due to …

What the Physician Needs to Know about Charcot Arthropathy and Ankle Fracture Treatment Dilemma: A Case Report and a Possible Medical Approach and …

M Tsatlidou, AV Vasiliadis… - Journal of Orthopaedic …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction: Charcot arthropathy consists of a rapid and destructive complication of the
joints following the loss of innervation caused by many complicated etiologies. Diabetic …