The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …

Optical microscopy has for centuries been a key tool to study living cells with minimum
invasiveness. The advent of single molecule techniques over the past two decades has …

Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Arbidol (ARB) is a Russian-made small indole-derivative molecule, licensed in Russia and
China for prophylaxis and treatment of influenza and other respiratory viral infections. It also …

A central paradigm within virology is that each viral particle largely behaves as an
independent infectious unit. Here, we demonstrate that clusters of enteroviral particles are …

Of the many pathogens that infect humans and animals, a large number use cells of the host
organism as protected sites for replication. To reach the relevant intracellular compartments …

Intestinal bacteria aid host health and limit bacterial pathogen colonization. However, the
influence of bacteria on enteric viruses is largely unknown. We depleted the intestinal …

We engineered covalently circularized nanodiscs (cNDs) which, compared with standard
nanodiscs, exhibit enhanced stability, defined diameter sizes and tunable shapes …

The hepatitis E virus (HEV) sheds into feces as nonenveloped virions but circulates in the
blood in a membrane-associated, quasi-enveloped form (eHEV). Since the eHEV virions …

Enteric viruses, including poliovirus and reovirus, encounter a vast microbial community in
the mammalian gastrointestinal tract, which has been shown to promote virus replication …