Major depressive disorder (MDD) is a leading cause of disability worldwide. After the first
episode, patients with remitted MDD have a 60% chance of experiencing a second episode …

BackgroundNumerous studies of resting-state functional imaging and voxel-based
morphometry (VBM) have revealed differences in specific brain regions of patients with …

Importance Biological psychiatry aims to understand mental disorders in terms of altered
neurobiological pathways. However, for one of the most prevalent and disabling mental …

Genetic (G) and environmental (E) factors are involved in the etiology and course of the
major psychoses (MP), ie major depressive disorder (MDD), bipolar disorder (BD) …

Brain structural covariance networks reflect covariation in morphology of different brain
areas and are thought to reflect common trajectories in brain development and maturation …

Background Childhood maltreatment is a leading environmental risk factor for an
unfavourable course of disease in major depressive disorder. Both maltreatment and major …

Objectives To elucidate the relationship between the course of bipolar disorder (BD) and
structural brain changes across the life span, we conducted a systematic review of …

Introduction More than a century of research on the neurobiological underpinnings of major
psychiatric disorders (major depressive disorder [MDD], bipolar disorder [BD], schizophrenia …

While research concerning brain structural biomarkers of major depressive disorder (MDD)
is continuously progressing, our state of knowledge regarding biomarkers of specific clinical …

 Psychoradiology is an emerging field that applies radiological imaging technologies to
psychiatric conditions. In the past three decades, brain imaging techniques have rapidly …