Cellular and molecular mechanisms in the pathogenesis of classical, vascular, and hypermobile ehlers‒danlos syndromes
N Chiarelli, M Ritelli, N Zoppi, M Colombi - Genes, 2019 - mdpi.com
The Ehlers‒Danlos syndromes (EDS) constitute a heterogenous group of connective tissue
disorders characterized by joint hypermobility, skin abnormalities, and vascular fragility. The …
disorders characterized by joint hypermobility, skin abnormalities, and vascular fragility. The …
Mesenchymal stem cells influence activation of hepatic stellate cells, and constitute a promising therapy for liver fibrosis
C Lee, M Kim, J Han, M Yoon, Y Jung - Biomedicines, 2021 - mdpi.com
Liver fibrosis is a common feature of chronic liver disease. Activated hepatic stellate cells
(HSCs) are the main drivers of extracellular matrix accumulation in liver fibrosis. Hence, a …
(HSCs) are the main drivers of extracellular matrix accumulation in liver fibrosis. Hence, a …
[HTML][HTML] Molecular pathways of liver regeneration: A comprehensive review
YV Kiseleva, SZ Antonyan, TS Zharikova… - World Journal of …, 2021 - ncbi.nlm.nih.gov
The liver is a unique parenchymal organ with a regenerative capacity allowing it to restore
up to 70% of its volume. Although knowledge of this phenomenon dates back to Greek …
up to 70% of its volume. Although knowledge of this phenomenon dates back to Greek …
Nanoparticle-based RNAi therapeutics targeting cancer stem cells: Update and prospective
Cancer stem cells (CSCs) are characterized by intrinsic self-renewal and tumorigenic
properties, and play important roles in tumor initiation, progression, and resistance to …
properties, and play important roles in tumor initiation, progression, and resistance to …
Biomarkers for Ehlers-Danlos syndromes: there is a role?
L Caliogna, V Guerrieri, S Annunziata, V Bina… - International Journal of …, 2021 - mdpi.com
Ehlers-Danlos syndromes (EDS) are an inherited heterogeneous group of connective tissue
disorders characterized by an abnormal collagen synthesis affecting skin, ligaments, joints …
disorders characterized by an abnormal collagen synthesis affecting skin, ligaments, joints …
[HTML][HTML] Role of hedgehog signaling related non-coding RNAs in developmental and pathological conditions
Z HajiEsmailPoor, P Tabnak, B Ahmadzadeh… - Biomedicine & …, 2022 - Elsevier
The hedgehog (Hh) signaling pathway is an evolutionarily conserved pathway that regulates
embryonic development in vertebrates. However, strong evidence suggests the role of its …
embryonic development in vertebrates. However, strong evidence suggests the role of its …
Overexpression of miR-125a-5p inhibits hepatocyte proliferation through the STAT3 regulation in vivo and in vitro
C Zhang, Y Zhao, Q Wang, J Qin, B Ye, C Xu… - International journal of …, 2022 - mdpi.com
microRNAs (miRNAs) are critically involved in liver regeneration (LR). miR-125a-5p (miR-
125a) is a tumor-suppressing miRNA, but its role in LR has not been studied. Our previous …
125a) is a tumor-suppressing miRNA, but its role in LR has not been studied. Our previous …
Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β‑catenin pathway
X Xiang, R Xiong, C Yu, L Deng, J Bie… - Oncology …, 2019 - spandidos-publications.com
A previous study by our group suggested that testis expressed 10 (Tex10) contributes to
tumor progression by promoting stem cell-like features in hepatocellular carcinoma …
tumor progression by promoting stem cell-like features in hepatocellular carcinoma …
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells
UT Arasu, AJ Deen, S Pasonen-Seppänen… - Cellular and Molecular …, 2020 - Springer
Intercellular communication is fundamental to the survival and maintenance of all
multicellular systems, whereas dysregulation of communication pathways can drive cancer …
multicellular systems, whereas dysregulation of communication pathways can drive cancer …
Changes in PPAR-γ expression are associated with microRNA profiles during fetal programming due to maternal overweight and obesity
N Gaytán-Pacheco, V Lima-Rogel… - Gynecologic and …, 2021 - karger.com
Background: There has been a global increase in the prevalence of obesity in pregnant
women in recent years. Animal studies have shown that intrauterine environment associated …
women in recent years. Animal studies have shown that intrauterine environment associated …