Dynamics of E. coli single stranded DNA binding (SSB) protein-DNA complexes
Single stranded DNA binding proteins (SSB) are essential to the cell as they stabilize
transiently open single stranded DNA (ssDNA) intermediates, recruit appropriate DNA …
transiently open single stranded DNA (ssDNA) intermediates, recruit appropriate DNA …
The mechanism of action of the SSB interactome reveals it is the first OB‐fold family of genome guardians in prokaryotes
PR Bianco - Protein science, 2021 - Wiley Online Library
The single‐stranded DNA binding protein (SSB) is essential to all aspects of DNA
metabolism in bacteria. This protein performs two distinct, but closely intertwined and …
metabolism in bacteria. This protein performs two distinct, but closely intertwined and …
Phase separation by ssDNA binding protein controlled via protein− protein and protein− DNA interactions
Bacterial single-stranded (ss) DNA-binding proteins (SSB) are essential for the replication
and maintenance of the genome. SSBs share a conserved ssDNA-binding domain, a less …
and maintenance of the genome. SSBs share a conserved ssDNA-binding domain, a less …
How glutamate promotes liquid-liquid phase separation and DNA binding cooperativity of E. coli SSB protein
E. coli single-stranded-DNA binding protein (EcSSB) displays nearest-neighbor (NN) and
non-nearest-neighbor (NNN)) cooperativity in binding ssDNA during genome maintenance …
non-nearest-neighbor (NNN)) cooperativity in binding ssDNA during genome maintenance …
Defining single molecular forces required for notch activation using nano yoyo
Notch signaling, involved in development and tissue homeostasis, is activated at the cell–
cell interface through ligand–receptor interactions. Previous studies have implicated …
cell interface through ligand–receptor interactions. Previous studies have implicated …
The Intrinsically Disordered C-terminal Tails of E. coli Single-Stranded DNA Binding Protein Regulate Cooperative Binding to Single-Stranded DNA
AG Kozlov, E Weiland, A Mittal, V Waldman… - Biophysical …, 2015 - cell.com
E. coli single strand DNA binding protein (SSB) is one of the key proteins in DNA replication,
recombination and repair. SSB functions as a homotetramer and binds ssDNA in different …
recombination and repair. SSB functions as a homotetramer and binds ssDNA in different …
Replication stalling activates SSB for recruitment of DNA damage tolerance factors
Translesion synthesis (TLS) polymerases bypass DNA lesions that block replicative
polymerases, allowing cells to tolerate DNA damage encountered during replication. It is …
polymerases, allowing cells to tolerate DNA damage encountered during replication. It is …
Multiprotein E. coli SSB–ssDNA complex shows both stable binding and rapid dissociation due to interprotein interactions
Abstract Escherichia coli SSB (Ec SSB) is a model single-stranded DNA (ssDNA) binding
protein critical in genome maintenance. Ec SSB forms homotetramers that wrap ssDNA in …
protein critical in genome maintenance. Ec SSB forms homotetramers that wrap ssDNA in …
Role of protein phosphorylation in the regulation of cell cycle and DNA-related processes in bacteria
In all living organisms, the phosphorylation of proteins modulates various aspects of their
functionalities. In eukaryotes, protein phosphorylation plays a key role in cell signaling, gene …
functionalities. In eukaryotes, protein phosphorylation plays a key role in cell signaling, gene …
The E. coli DNA replication fork
DNA replication in Escherichia coli initiates at oriC, the origin of replication and proceeds
bidirectionally, resulting in two replication forks that travel in opposite directions from the …
bidirectionally, resulting in two replication forks that travel in opposite directions from the …