Recent progress in red blood cells-derived particles as novel bioinspired drug delivery systems: challenges and strategies for clinical translation

A Vincy, S Mazumder, Amrita, I Banerjee… - Frontiers in …, 2022 - frontiersin.org
Red Blood Cells (RBCs)-derived particles are an emerging group of novel drug delivery
systems. The natural attributes of RBCs make them potential candidates for use as a drug …

Recent advances with erythrocytes as therapeutics carriers

RH Barhaghtalab, HT Aiyelabegan, H Maleki… - International Journal of …, 2024 - Elsevier
Erythrocytes have gained popularity as a natural option for in vivo drug delivery due to their
advantages, which include lengthy circulation times, biocompatibility, and biodegradability …

Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction

F Ferro, R Spelat, A Pandit, JL Martin-Ventura… - Trends in Molecular …, 2024 - cell.com
Protein glycosylation controls cell–cell and cell–extracellular matrix (ECM) communication in
immune, vascular, and inflammatory processes, underlining the critical role of this process in …

Drug-loaded erythrocytes: Modern approaches for advanced drug delivery for clinical use

K Berikkhanova, E Taigulov, Z Bokebaev, A Kusainov… - Heliyon, 2024 - cell.com
Scientific organizations worldwide are striving to create drug delivery systems that provide a
high local concentration of a drug in pathological tissue without side effects on healthy …

Red Blood Cell-Derived Extracellular Vesicles: An Overview of Current Research Progress, Challenges, and Opportunities

SR Ma, HF Xia, P Gong, ZL Yu - Biomedicines, 2023 - mdpi.com
Red blood cell-derived extracellular vesicles (RBC EVs) are small, spherical fragments
released from red blood cells. These vesicles, similar to EVs derived from other cell types …

Erythrocyte Membrane Camouflaged Nanotheranostics for Optical Molecular Imaging‐Escorted Self‐Oxygenation Photodynamic Therapy

Y Wan, C Li, LH Fu, T Feng, Y Zhang, Y Li, J Lin… - Small, 2024 - Wiley Online Library
Hypoxic tumor microenvironment (TME) hampers the application of oxygen (O2)‐dependent
photodynamic therapy (PDT) in solid tumors. To address this problem, a biomimetic …

Morphological characteristics, hemoglobin content, and membrane mechanical properties of red blood cell delivery systems

T Lu, CH Lee, B Anvari - ACS applied materials & interfaces, 2022 - ACS Publications
Red blood cell (RBC)-based systems are under extensive development as platforms for the
delivery of various biomedical agents. While the importance of the membrane biochemical …

Membrane cholesterol enrichment and folic acid functionalization lead to increased accumulation of erythrocyte-derived optical nano-constructs within the ovarian …

CH Lee, J Mac, T Hanley, S Zaman… - … , Biology and Medicine, 2024 - Elsevier
Cytoreductive surgery remains as the gold standard to treat ovarian cancer, but with limited
efficacy since not all tumors can be intraoperatively visualized for resection. We have …

Self-assembly behavior and sustained drug release properties of amphiphilic poly (amino acid) s

Z Hu, J Wang, S Han, J Hu, A Reheman - New Journal of Chemistry, 2022 - pubs.rsc.org
In this study, a series of poly (amino acid) s materials with amphiphilic properties were
synthesized by ring-opening polymerization. In specific solvents, macromolecules can self …

Preclinical and clinical developments in enzyme-loaded red blood cells: an update

M Bianchi, L Rossi, F Pierigè, S Biagiotti… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction We have previously described the preclinical developments in enzyme-loaded
red blood cells to be used in the treatment of several rare diseases, as well as in chronic …