Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …

Molecular networking is a tandem mass spectrometry (MS/MS) data organizational
approach that has been recently introduced in the drug discovery, metabolomics, and …

Abstract Global Natural Product Social Molecular Networking (GNPS) is an interactive online
small molecule–focused tandem mass spectrometry (MS2) data curation and analysis …

The high-performance liquid chromatography-mass spectrometry (LC-MS) technique is
widely applied to routine analysis in many matrices. Despite the enormous application of …

Sample preparation is considered as the bottleneck step in bioanalysis because each
biological matrix has its own unique challenges and complexity. Competent sample …

Observational studies from all over the world continue to find high prevalence rates of
vitamin D insufficiency and deficiency in many populations, including pregnant women …

Cancers have an altered metabolism, and there is interest in understanding precisely how
oncogenic transformation alters cellular metabolism and how these metabolic alterations …

Sample treatment is so crucial in pharmaceutical and biomedical analysis. Proper sample
preparation protects the analytical instrument, increases the sensitivity, and enhances the …

Ischemic stroke is a sudden loss of brain function due to the reduction of blood flow. Brain
tissues cease to function with subsequent activation of the ischemic cascade. Metabolomics …

Our skin, our belongings, the world surrounding us, and the environment we live in are
covered with molecular traces. Detecting and characterizing these molecular traces is …