Matrix metalloproteinases (MMPs) are a family of nine or more highly homologous Zn++
endopeptidases that collectively cleave most if not all of the constituents of the extracellular …

Proteolytic enzymes have many physiological functions, ranging from generalized protein
digestion to more specific regulated processes such as the activation of zymogens, blood …

Specificity of Proteolysis presents a survey and conclusions on the action or proteinases-
enzymes which are cleaving proteins or peptides. The specificity of proteinases which is …

The pre-eminent reference on coagulation disorders is now in its thoroughly updated Fifth
Edition. Written by more than 160 of the world's foremost authorities, this encyclopedic …

The amino acid sequence of a 90-residue segment of human pregnancy zone protein
containing its bait region has been determined. Human α 2-macroglobulin, human …

The primary structure of the tetrameric plasma glycoprotein human alpha 2-macroglobulin
has been determined. The identical subunits contain 1451 amino acid residues …

Brains of hibernating mammals are protected against a variety of insults that are detrimental
to humans and other nonhibernating species. Such protection is associated with a number …

Human kallikrein 5 (KLK5) is a member of the human kallikrein gene family of serine
proteases. Preliminary results indicate that the protein, hK5, may be a potential serological …

The interaction between human fibroblast collagenase and five mammalian a-
macroglobulins (human α 2-macroglobulin and pregnancy zone protein, rat α 1-and α 2 …

Osteoarthritis is characterized by the loss of aggrecan and collagen from the cartilage
extracellular matrix. The proteinases responsible for the breakdown of cartilage aggrecan …