Background Epilepsy is a common and debilitating consequence of traumatic brain injury
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …

Epilepsy is a group of chronic neurological disorders that have diverse etiologies but are
commonly characterized by spontaneous seizures and behavioral comorbidities. Although …

As a crucial component of brain innate immunity, neuroinflammation initially contributes to
neuronal tissue repair and maintenance. However, chronic inflammatory processes within …

Epilepsy is a common chronic neurological disorder affecting approximately 8 out of 1000
people. Its pathophysiology, however, has remained elusive in many regards …

CNS injuries such as trauma, stroke, viral infection, febrile seizures, status epilepticus
occurring either in infancy or during a lifetime are considered common risk factors for …

In the present study, the expression of pro-inflammatory transcripts was assessed across the
brain of mice having undertaken pilocarpine-induced seizures. Pilocarpine-induced marked …

Epilepsy is a brain disease associated with epileptic seizures as well as with
neurobehavioral outcomes of this condition. In the last century, inflammation emerged as a …

Recently, the role of inflammation has attracted great attention in the pathogenesis of mesial
temporal lobe epilepsy (MTLE), and microRNAs start to emerge as promising new players in …

Here we study the role of a pleiotropic pro-inflammatory cytokine, interleukin-6 (IL-6), in
epilepsy. To examine this problem, we used human recombinant IL-6 applied intranasally …

Vascular endothelial growth factor (VEGF) is a vascular growth factor which induces
angiogenesis (the development of new blood vessels), vascular permeability, and …