[HTML][HTML] Antiparasitics in animal health: quo vadis?

PM Selzer, C Epe - Trends in parasitology, 2021 - cell.com
Antiparasitics acting on endo-or ectoparasites represent the second largest segment of the
global animal health market, accounting for 23% of market share. However, relatively few …

[HTML][HTML] Heartworm disease–Overview, intervention, and industry perspective

S Noack, J Harrington, DS Carithers… - International Journal for …, 2021 - Elsevier
Dirofilaria immitis, also known as heartworm, is a major parasitic threat for dogs and cats
around the world. Because of its impact on the health and welfare of companion animals …

[HTML][HTML] Genomic landscape of drug response reveals mediators of anthelmintic resistance

SR Doyle, R Laing, D Bartley, A Morrison, N Holroyd… - Cell Reports, 2022 - cell.com
Like other pathogens, parasitic helminths can rapidly evolve resistance to drug treatment.
Understanding the genetic basis of anthelmintic drug resistance in parasitic nematodes is …

[HTML][HTML] Perspectives on the utility of moxidectin for the control of parasitic nematodes in the face of developing anthelmintic resistance

RK Prichard, TG Geary - International Journal for Parasitology: Drugs and …, 2019 - Elsevier
Macrocyclic lactone (ML) anthelmintics are the most important class of anthelmintics
because of our high dependence on them for the control of nematode parasites and some …

[HTML][HTML] Refugia and anthelmintic resistance: concepts and challenges

JE Hodgkinson, RM Kaplan, F Kenyon… - International Journal for …, 2019 - Elsevier
Anthelmintic resistance is a threat to global food security. In order to alleviate the selection
pressure for resistance and maintain drug efficacy, management strategies increasingly aim …

[HTML][HTML] Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance

AC Kotze, JS Gilleard, SR Doyle, RK Prichard - International Journal for …, 2020 - Elsevier
Anthelmintic resistance is a significant threat to livestock production systems worldwide and
is emerging as an important issue in companion animal parasite management. It is also an …

[HTML][HTML] Macrocyclic lactone resistance in Dirofilaria immitis: risks for prevention of heartworm disease

RK Prichard - International Journal for Parasitology, 2021 - Elsevier
Heartworm disease, caused by Dirofilaria immitis, can be lethal in dogs and cats. It is
transmitted by mosquitoes, and occurs in many parts of the world. Prevention relies on …

[HTML][HTML] Leishmania infantum and Dirofilaria immitis infections in Italy, 2009–2019: changing distribution patterns

J Mendoza-Roldan, G Benelli, R Panarese, R Iatta… - Parasites & vectors, 2020 - Springer
Background For long time, canine leishmaniosis (CanL) was considered endemic in the
southern, central, and insular regions of Italy, whereas heartworm disease (HW) caused by …

Best practices for preventing vector-borne diseases in dogs and humans

F Dantas-Torres, D Otranto - Trends in parasitology, 2016 - cell.com
Vector-borne diseases constitute a diversified group of illnesses, which are caused by a
multitude of pathogens transmitted by arthropod vectors, such as mosquitoes, fleas, ticks …

[HTML][HTML] Profiling extracellular vesicle release by the filarial nematode Brugia malayi reveals sex-specific differences in cargo and a sensitivity to ivermectin

H Harischandra, W Yuan, HJ Loghry… - PLoS neglected …, 2018 - journals.plos.org
The filarial nematode Brugia malayi is an etiological agent of Lymphatic Filariasis. The
capability of B. malayi and other parasitic nematodes to modulate host biology is recognized …