Follicle-stimulating hormone signaling is essential for the initiation and early stages of
spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli …

Parenthood at an older age is becoming a trend among men, especially in the most
developed societies. Aging has a significant impact on male fertility. Older men exhibit …

Sertoli cells play a central role in spermatogenesis. They maintain the blood-testis barrier,
an essential feature of seminiferous tubules which creates the proper environment for the …

The physiological process of male reproduction relies on the orchestration of
neuroendocrine, immune, and energy metabolism. Spermatogenesis is controlled by the …

In recent years, the mammalian target of rapamycin (mTOR) has emerged as a master
integrator of upstream inputs, such as amino acids, growth factors and insulin availability …

Infertility is becoming a chronic and emerging problem in the world. There is a resistant
stigma that this health condition is mostly due to the female, although the literature supports …

Mammalian target of rapamycin (mTOR) is a central regulator of cellular metabolic
phenotype and is involved in virtually all aspects of cellular function. It integrates not only …

The permanent exposure to environmental contaminants promoting weight gain (ie,
obesogens) has raised serious health concerns. Evidence suggests that obesogens are one …

Keloid is a fibro-proliferative skin disorder with tumor-like behavior and dependence on
anaerobic glycolysis (the Warburg effect), but its exact pathogenesis is unknown. Although …

The current scenario of male infertility is not yet fully elucidated; however, there is increasing
evidence that it is associated with the widespread exposure to endocrine-disrupting …