[HTML][HTML] How vascular smooth muscle cell phenotype switching contributes to vascular disease

G Cao, X Xuan, J Hu, R Zhang, H Jin… - Cell Communication and …, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …

Epidemiology and management of aortic disease: aortic aneurysms and acute aortic syndromes

E Bossone, KA Eagle - Nature Reviews Cardiology, 2021 - nature.com
The aorta is the 'greatest artery', through which oxygenated blood is delivered from the left
ventricle to end organs with each cardiac cycle (200 million litres of blood transported in an …

2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint …

Writing Committee Members, EM Isselbacher… - Journal of the American …, 2022 - jacc.org
Abstract Aim The “2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic
Disease” provides recommendations to guide clinicians in the diagnosis, genetic evaluation …

Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation

Z Tian, Y Zhang, Z Zheng, M Zhang, T Zhang, J Jin… - Cell host & …, 2022 - cell.com
Abdominal aortic aneurysm (AAA) is an insidious and lethal vascular disease that lacks
effective nonsurgical interventions. Gut microbiota dysbiosis plays key roles in many …

[HTML][HTML] Reporting standards for endovascular aortic repair of aneurysms involving the renal-mesenteric arteries

GS Oderich, TL Forbes, R Chaer, MG Davies… - Journal of vascular …, 2021 - Elsevier
Endovascular aortic aneurysm repair of complex aortic aneurysms requires incorporation of
side branches using specially designed aortic stent grafts with fenestrations, directional …

Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

[HTML][HTML] Cardiovascular diseases in sub-Saharan Africa compared to high-income countries: an epidemiological perspective

MF Yuyun, K Sliwa, AP Kengne, AO Mocumbi… - Global …, 2020 - ncbi.nlm.nih.gov
Non-communicable diseases (NCDs) are the second common cause of death in sub-
Saharan Africa (SSA) accounting for about 35% of all deaths, after a composite of …

[HTML][HTML] Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

T Roychowdhury, D Klarin, MG Levin, JM Spin… - Nature …, 2023 - nature.com
Abdominal aortic aneurysm (AAA) is a common disease with substantial heritability. In this
study, we performed a genome-wide association meta-analysis from 14 discovery cohorts …

Screening for abdominal aortic aneurysm: US preventive services task force recommendation statement

DK Owens, KW Davidson, AH Krist, MJ Barry… - Jama, 2019 - jamanetwork.com
Importance An abdominal aortic aneurysm (AAA) is typically defined as aortic enlargement
with a diameter of 3.0 cm or larger. The prevalence of AAA has declined over the past 2 …

[HTML][HTML] Management of abdominal aortic aneurysms

A Schanzer, GS Oderich - New England Journal of Medicine, 2021 - Mass Medical Soc
Key Clinical Points Management of Abdominal Aortic Aneurysms Risk factors for abdominal
aortic aneurysm include advanced age, male sex, family history, previous or current use of …