Lessons Learned for Pathogenesis, Immunology, and Disease of Erythrocytic Parasites: Plasmodium and Babesia

V Djokic, SC Rocha, N Parveen - Frontiers in cellular and infection …, 2021 - frontiersin.org
Malaria caused by Plasmodium species and transmitted by Anopheles mosquitoes affects
large human populations, while Ixodes ticks transmit Babesia species and cause …

Human babesiosis: recent advances and future challenges

CA Lobo, M Singh, M Rodriguez - Current opinion in hematology, 2020 - journals.lww.com
New Babesia species have been identified globally, suggesting that the epidemiology of this
disease is rapidly changing, making it clear that human babesiosis is a serious public health …

Comparative and functional genomics of the protozoan parasite Babesia divergens highlighting the invasion and egress processes

LM Gonzalez, K Estrada, R Grande… - PLoS neglected …, 2019 - journals.plos.org
Babesiosis is considered an emerging disease because its incidence has significantly
increased in the last 30 years, providing evidence of the expanding range of this rare but …

Babesia microti Infection Changes Host Spleen Architecture and Is Cleared by a Th1 Immune Response

V Djokic, L Akoolo, N Parveen - Frontiers in Microbiology, 2018 - frontiersin.org
Babesia microti is a malaria-like parasite, which infects∼ 2000 people annually, such that
babesiosis is now a notifiable disease in the United States. Immunocompetent individuals …

Identification and characterization of extracellular vesicles from red cells infected with Babesia divergens and Babesia microti

D Beri, M Rodriguez, M Singh, Y Liu… - Frontiers in Cellular …, 2022 - frontiersin.org
Babesiosis is a zoonosis and an important blood-borne human parasitic infection that has
gained attention because of its growing infection rate in humans by transfer from animal …

Kinetics of the invasion and egress processes of Babesia divergens, observed by time-lapse video microscopy

E Sevilla, LM González, D Luque, J Gray, E Montero - Scientific Reports, 2018 - nature.com
Based on confocal fluorescence and bright field video microscopy, we present detailed
observations on the processes of invasion and egress of erythrocytes by the apicomplexan …

Comparative single-cell transcriptional atlases of Babesia species reveal conserved and species-specific expression profiles

Y Rezvani, CD Keroack, B Elsworth, A Arriojas… - PLoS …, 2022 - journals.plos.org
Babesia is a genus of apicomplexan parasites that infect red blood cells in vertebrate hosts.
Pathology occurs during rapid replication cycles in the asexual blood stage of infection …

A framework for signaling throughout the life cycle of Babesia species

B Elsworth, MT Duraisingh - Molecular microbiology, 2021 - Wiley Online Library
Babesia species are tick‐borne intracellular parasites that infect the red blood cells of their
mammalian host, leading to severe or fatal disease. Babesia spp. infect a wide range of …

Babesia divergens: A Drive to Survive

CA Lobo, JR Cursino-Santos, M Singh, M Rodriguez - Pathogens, 2019 - mdpi.com
Babesia divergens is an obligate intracellular protozoan parasite that causes zoonotic
disease. Central to its pathogenesis is the ability of the parasite to invade host red blood …

Global metabolomic profiling of host red blood cells infected with Babesia divergens reveals novel antiparasitic target pathways

D Beri, M Singh, M Rodriguez, N Goyal… - Microbiology …, 2023 - Am Soc Microbiol
Babesia divergens is an apicomplexan parasite that infects human red blood cells (RBCs),
initiating cycles of invasion, replication, and egress, resulting in extensive metabolic …