[HTML][HTML] Using big sequencing data to identify chronic SARS-Coronavirus-2 infections
The evolution of SARS-Coronavirus-2 (SARS-CoV-2) has been characterized by the
periodic emergence of highly divergent variants. One leading hypothesis suggests these …
periodic emergence of highly divergent variants. One leading hypothesis suggests these …
[HTML][HTML] Evolution of the SARS-CoV-2 Omicron Variants: Genetic Impact on Viral Fitness
W Liu, Z Huang, J Xiao, Y Wu, N Xia, Q Yuan - Viruses, 2024 - mdpi.com
Over the last three years, the pandemic of COVID-19 has had a significant impact on
people's lives and the global economy. The incessant emergence of variant strains has …
people's lives and the global economy. The incessant emergence of variant strains has …
[HTML][HTML] Sotrovimab: A Review of Its Efficacy against SARS-CoV-2 Variants
Among the anti-Spike monoclonal antibodies (mAbs), the S-309 derivative sotrovimab was
the most successful in having the longest temporal window of clinical use, showing a high …
the most successful in having the longest temporal window of clinical use, showing a high …
[HTML][HTML] Evolving spike-protein N-glycosylation in SARS-CoV-2 variants
Abstract Since> 3 years, SARS-CoV-2 has plunged humans into a colossal pandemic.
Henceforth, multiple waves of infection have swept through the human population, led by …
Henceforth, multiple waves of infection have swept through the human population, led by …
[HTML][HTML] A bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB. 1.16, BQ. 1.1 and sarbecoviruses
Y Wang, A Hao, P Ji, Y Ma, Z Zhang, J Chen… - Nature …, 2024 - nature.com
Abstract The Omicron subvariants BQ. 1.1, XBB. 1.5, and XBB. 1.16 of SARS-CoV-2 are
known for their adeptness at evading immune responses. Here, we isolate a neutralizing …
known for their adeptness at evading immune responses. Here, we isolate a neutralizing …
[HTML][HTML] A Candidate DNA Vaccine Encoding the Native SARS-CoV-2 Spike Protein Induces Anti-Subdomain 1 Antibodies
A Frische, V Gunalan, KA Krogfelt, A Fomsgaard… - Vaccines, 2023 - mdpi.com
The ideal vaccine against viral infections should elicit antibody responses that protect
against divergent strains. Designing broadly protective vaccines against SARS-CoV-2 and …
against divergent strains. Designing broadly protective vaccines against SARS-CoV-2 and …
ACE2 mimetic antibody potently neutralizes all SARS-CoV-2 variants and fully protects in XBB. 1.5 challenged monkeys
C Fenwick, P Turelli, Y Duhoo, K Lau, C Herate… - bioRxiv, 2023 - biorxiv.org
The rapid evolution of SARS-CoV-2 to variants with improved transmission efficiency and
reduced sensitivity to vaccine-induced humoral immunity has abolished the protective effect …
reduced sensitivity to vaccine-induced humoral immunity has abolished the protective effect …
[HTML][HTML] Antigen-Heterologous Vaccination Regimen Triggers Alternate Antibody Targeting in SARS-CoV-2-DNA-Vaccinated Mice
A Frische, KA Krogfelt, A Fomsgaard, R Lassaunière - Vaccines, 2024 - mdpi.com
An in-depth analysis of antibody epitopes following vaccination with different regimens
provides important insight for developing future vaccine strategies. B-cell epitopes …
provides important insight for developing future vaccine strategies. B-cell epitopes …
[HTML][HTML] Combining iCn3D and NextStrain to create a novel undergraduate research experience around SARS-CoV-2 variants and commercial antibodies
Undergraduate research experiences are increasingly important in biology education with
efforts underway to provide more projects by embedded them in a course. The shift to online …
efforts underway to provide more projects by embedded them in a course. The shift to online …