Type 1 diabetes (T1D) results from destruction of pancreatic beta cells by T cells of the
immune system. Despite improvements in insulin analogs and continuous blood glucose …

Abstract Type 1 Diabetes (T1D) is an autoimmune disease characterized by the pancreatic
infiltration of immune cells resulting in T cell-mediated destruction of the insulin-producing …

Beta cells from nondiabetic mice transfer secretory vesicles to phagocytic cells. The passage
was shown in culture studies where the transfer was probed with CD4 T cells reactive to …

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by hyperglycemia
due to progressive immune-mediated destruction of insulin-producing pancreatic islet β …

Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by the destruction of
pancreatic beta cells, in which immune system disorder plays an important role. Finding a …

Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-
producing pancreatic β-cells by their own immune system, resulting in lifelong insulin …

Type 1 diabetes (T1D) is an autoimmune disease in which immune-mediated targeting and
destruction of insulin-producing pancreatic islet β cells leads to chronic hyperglycemia …

Diabetes can be simply classified into type 1 diabetes mellitus and type 2 diabetes mellitus.
Zinc transporter 8 (ZnT8), a novel islet autoantigen, is specifically expressed in insulin …

Abstract Objective Zinc transporter 8 (ZnT8) is a major humoral target in human type 1
diabetes (T1D). Polymorphic variants of Slc30A8, which encodes ZnT8, are also associated …

Abstract Zinc transporter 8 (ZnT8), a protein highly specific to pancreatic insulin-producing
beta cells, is vital for the biosynthesis and secretion of insulin. ZnT8 autoantibodies (ZnT8A) …