Unexplained male infertility is a diagnosis reserved for men in whom routine semen
analyses results are within normal values and physical as well as endocrine abnormalities …

New chemicals are being added each year to the existing burden of toxic substances in the
environment. This has led to increased pollution of ecosystems as well as deterioration of …

Highlights•Sperm nuclear and chromatin abnormalities are common among infertile men
and are known to influence natural reproduction.•The haploid paternal genome provides the …

Background The initial step in the diagnostic investigation of male infertility has been
traditionally based on the conventional seminal profile. However, there are significant …

The process of cryopreservation impairs sperm cell function, potentially leading to a
reduction in fertility. The objectives of the present study were to evaluate the effects that …

STUDY QUESTION Is there an association between sperm DNA damage, measured by
three different assays, sperm nuclear protein content and clinical outcomes in assisted …

DNA fragmentation, or the accumulation of single-and double-strand DNA breaks, is a
common property of sperm, and an increase in the level of sperm DNA fragmentation is …

Diagnosis of sperm DNA integrity of semen sample is important for consistently high
reproductive efficiency. The conventional parameters of semen analysis take into account …

In an age when a small quantity of sperm can lead to pregnancy through in vitro fertilization
or intracytoplasmic sperm injection, selecting healthy sperm is important. Sperm DNA …

Our ability to screen the structural and functional integrity of the spermatozoon in vitro has
increased markedly over the past decades, but our capacity to estimate the fertility of a …