The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds
M Van den Berg, LS Birnbaum, M Denison… - Toxicological …, 2006 - academic.oup.com
Abstract In June 2005, a World Health Organization (WHO)-International Programme on
Chemical Safety expert meeting was held in Geneva during which the toxic equivalency …
Chemical Safety expert meeting was held in Geneva during which the toxic equivalency …
Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife.
M Van den Berg, L Birnbaum, AT Bosveld… - Environmental …, 1998 - ehp.niehs.nih.gov
An expert meeting was organized by the World Health Organization (WHO) and held in
Stockholm on 15-18 June 1997. The objective of this meeting was to derive consensus toxic …
Stockholm on 15-18 June 1997. The objective of this meeting was to derive consensus toxic …
Bioanalytical screening methods for dioxins and dioxin-like compounds—a review of bioassay/biomarker technology
PA Behnisch, K Hosoe, S Sakai - Environment International, 2001 - Elsevier
Determination of environmental pollutants utilizing biodetectors such as bioassays,
biomarkers, enzyme immunoassays (EIAs), or other bioanalytical tools is a continuously …
biomarkers, enzyme immunoassays (EIAs), or other bioanalytical tools is a continuously …
The toxicological effects of halogenated naphthalenes: a review of aryl hydrocarbon receptor-mediated (dioxin-like) relative potency factors
J Falandysz, A Fernandes… - … Science and Health …, 2014 - Taylor & Francis
There is no doubt that chloronaphthalenes (PCNs) and their brominated counterparts
(PBNs) are dioxin-like compounds, but there is less evidence for mixed bromo …
(PBNs) are dioxin-like compounds, but there is less evidence for mixed bromo …
Megavariate analysis of environmental QSAR data. Part I–A basic framework founded on principal component analysis (PCA), partial least squares (PLS), and …
L Eriksson, PL Andersson, E Johansson, M Tysklind - Molecular diversity, 2006 - Springer
This paper introduces principal component analysis (PCA), partial least squares projections
to latent structures (PLS), and statistical molecular design (SMD) as useful tools in deriving …
to latent structures (PLS), and statistical molecular design (SMD) as useful tools in deriving …
Multivariate design and modeling in QSAR
L Eriksson, E Johansson - Chemometrics and intelligent laboratory systems, 1996 - Elsevier
Quantitative structure-activity relationship (QSAR) modeling provides a rational basis for
understanding mechanisms of biological performance and how to alter chemical structures …
understanding mechanisms of biological performance and how to alter chemical structures …
Analyzing toxicity through electrophilicity
The toxicological structure-activity relationships are investigated using conceptual DFT
based descriptors like global and local electrophilicities. In the present work the usefulness …
based descriptors like global and local electrophilicities. In the present work the usefulness …
Characterization of the H4IIE rat hepatoma cell bioassay for evaluation of environmental samples containing polynuclear aromatic hydrocarbons (PAHs)
The H4IIE rat hepatoma cell bioassay has been extensively used to assess the toxic
equivalents (TEQs) of complex mixtures of halogenated aromatic hydrocarbons in …
equivalents (TEQs) of complex mixtures of halogenated aromatic hydrocarbons in …
Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment
ME Hahn - Science of the Total Environment, 2002 - Elsevier
The presence of toxic chemical contaminants in some marine organisms, including those
consumed by humans, is well known. Monitoring the levels of such contaminants and their …
consumed by humans, is well known. Monitoring the levels of such contaminants and their …
Environmental contaminants and biomarker responses in fish from the Rio Grande and its US tributaries: spatial and temporal trends
CJ Schmitt, JE Hinck, VS Blazer, ND Denslow… - Science of the total …, 2005 - Elsevier
We collected, examined, and analyzed 368 fish of seven species from 10 sites on rivers of
the Rio Grande Basin (RGB) during late 1997 and early 1998 to document temporal and …
the Rio Grande Basin (RGB) during late 1997 and early 1998 to document temporal and …