Inflammatory response to regulated cell death in gout and its functional implications

J Zhao, K Wei, P Jiang, C Chang, L Xu, L Xu… - Frontiers in …, 2022 - frontiersin.org
Gout, a chronic inflammatory arthritis disease, is characterized by hyperuricemia and caused
by interactions between genetic, epigenetic, and metabolic factors. Acute gout symptoms are …

Role of NLRP3 in the pathogenesis and treatment of gout arthritis

Y Liu, J Wang, J Li - Frontiers in Immunology, 2023 - frontiersin.org
Gout arthritis (GA) is a common and curable type of inflammatory arthritis that has been
attributed to a combination of genetic, environmental and metabolic factors. Chronic …

Anti-inflammatory and immunoregulatory action of sesquiterpene lactones

A Paço, T Brás, JO Santos, P Sampaio, AC Gomes… - Molecules, 2022 - mdpi.com
Sesquiterpene lactones (SL), characterized by their high prevalence in the Asteraceae
family, are one of the major groups of secondary metabolites found in plants. Researchers …

Sesquiterpene lactones: Promising natural compounds to fight inflammation

MS Matos, JD Anastácio, C Nunes dos Santos - Pharmaceutics, 2021 - mdpi.com
Inflammation is a crucial and complex process that reestablishes the physiological state after
a noxious stimulus. In pathological conditions the inflammatory state may persist, leading to …

Linking endophytic fungi to medicinal plants therapeutic activity. A case study on Asteraceae

G Caruso, MT Abdelhamid, A Kalisz, A Sekara - Agriculture, 2020 - mdpi.com
Endophytes are isolated from every plant species investigated to date, so the metabolome
coevolution has been affecting the plants'(microbiota) ethnobotanic, especially therapeutic …

[HTML][HTML] Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering

B Zhang, H Xu, J Chen, X Zhu, Y Xue, Y Yang, J Ao… - Theranostics, 2021 - ncbi.nlm.nih.gov
Gout is a common metabolic disease with growing burden, caused by monosodium urate
(MSU) microcrystal deposition. In situ and chemical-specific histological identification of …

Apamin from bee venom suppresses inflammation in a murine model of gouty arthritis

YM Lee, SN Cho, E Son, CH Song, DS Kim - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Bee venom (BV) has been used for the treatment of
inflammatory diseases, such as rheumatoid arthritis, and for the relief of pain in traditional …

IL-33 enhances macrophage release of IL-1β and promotes pain and inflammation in gouty arthritis

V Fattori, L Staurengo-Ferrari, TH Zaninelli… - Inflammation …, 2020 - Springer
Objective To investigate the role of IL-33 in gouty arthritis. Material 174 Balb/c (wild-type)
and 54 ST2−/− mice were used in this study. In vitro experiments were conducted in bone …

Tu-Teng-Cao Extract Alleviates Monosodium Urate‐Induced Acute Gouty Arthritis in Rats by Inhibiting Uric Acid and Inflammation

R Yao, Z Geng, X Mao, Y Bao, S Guo… - Evidence‐Based …, 2020 - Wiley Online Library
Gouty arthritis is an inflammatory joint disease closely related to hyperuricemia. It is
characterized by deposition of monosodium urate crystals in the joints, resulting in an …

Asteraceae plants as sources of compounds against leishmaniasis and Chagas disease

RN Moraes Neto, RFB Setúbal, TMM Higino… - Frontiers in …, 2019 - frontiersin.org
Leishmaniasis and Chagas disease cause great impact on social and economic aspects of
people living in developing countries. The treatments for these diseases are based on the …