Antioxidants and inflammatory disease: synthetic and natural antioxidants with anti-inflammatory activity

AA Geronikaki, AM Gavalas - Combinatorial chemistry & high …, 2006 - ingentaconnect.com
Oxidants play a significant role in the pathogenesis of a number of disorders such as
inflammation, rheumatoid arthritis, asthma, psoriasis and contact dermatitis leading to …

Leukocytes in diabetic retinopathy

R Chibber, BM Ben-Mahmud, S Chibber… - Current diabetes …, 2007 - ingentaconnect.com
Diabetic retinopathy is one of the most common diabetic complications, and is a major cause
of new blindness in the working-age population of developed countries. Progression of …

Piperine inhibits TNF-α induced adhesion of neutrophils to endothelial monolayer through suppression of NF-κB and IκB kinase activation

S Kumar, V Singhal, R Roshan, A Sharma… - European journal of …, 2007 - Elsevier
Piperine displays antipyretic, analgesic, insecticidal and anti-inflammatory activities. It is the
first amide to be isolated from Piper species. In the process of identifying non-steroidal anti …

Recent development of lipoxygenase inhibitors as anti-inflammatory agents

C Hu, S Ma - Medchemcomm, 2018 - pubs.rsc.org
Inflammation is favorable in most cases, because it is a kind of body defensive response to
external stimuli; sometimes, inflammation is also harmful, such as attacks on the body's own …

Isoliquiritigenin inhibits IκB kinase activity and ROS generation to block TNF-α induced expression of cell adhesion molecules on human endothelial cells

S Kumar, A Sharma, B Madan, V Singhal… - Biochemical …, 2007 - Elsevier
Isoliquiritigenin (ILTG) is a flavonoid with chalcone structure (4, 2′, 4′-
trihydroxychalcone), an active component present in plants like Glycyrrhiza and Dalbergia …

[PDF][PDF] Pharmacologically potentials of different substituted coumarin derivatives

M Asif - Chem. Int, 2015 - academia.edu
Coumarins are well recognized naturally occurring compounds which isolated and present
in large number of compounds in the plant kingdom. Mostly occur in higher plants, richest …

Tandem sp3 C–H Functionlization/Decarboxylation of 2-Alkylazaarenes with Coumarin-3-carboxylic Acids

L Xu, Z Shao, L Wang, J Xiao - Organic letters, 2014 - ACS Publications
The catalyst-free sp3 C–H functionalization of 2-alkylazaarenes has been achieved in the
reaction with (thio) coumarin-3-carboxylic acids. Followed by a tandem decarboxylation, this …

Novel Aromatic Ester from Piper longum and Its Analogues Inhibit Expression of Cell Adhesion Molecules on Endothelial Cells

S Kumar, P Arya, C Mukherjee, BK Singh, N Singh… - Biochemistry, 2005 - ACS Publications
We report here the isolation and characterization of two active principles, ethyl 3 ', 4 ', 5 '-
trimethoxycinnamate (1) and piperine (2), from the combined hexane and chloroform …

Structural modifications of coumarin derivatives: Determination of antioxidant and lipoxygenase (LOX) inhibitory activity

M Roussaki, K Zelianaios, E Kavetsou… - Bioorganic & medicinal …, 2014 - Elsevier
In the present project, a series of coumarin analogues, were synthesised and evaluated for
their antioxidant and soybean lipoxygenase inhibitory activity. A variety of structural …

Platelet expression of CD40/CD40 ligand and its relation to inflammatory markers and adhesion molecules in patients with atrial fibrillation

M Hammwöhner, A Ittenson, J Dierkes… - Experimental …, 2007 - journals.sagepub.com
Recent studies suggest the importance of prothrombotic and proinflammatory cascades in
vascular thrombus formation. However, the impact of platelet CD40 and CD40 ligand …