[HTML][HTML] Molecular and cellular heterogeneity in rheumatoid arthritis: mechanisms and clinical implications

J Zhao, S Guo, SJ Schrodi, D He - Frontiers in immunology, 2021 - frontiersin.org
Rheumatoid arthritis is an autoimmune disease that exhibits significant clinical
heterogeneity. There are various treatments for rheumatoid arthritis, including disease …

Genetic implications in the pathogenesis of rheumatoid arthritis; an updated review

J Karami, S Aslani, A Jamshidi, M Garshasbi… - Gene, 2019 - Elsevier
Three important factors, including genetics, environment factors and autoimmunity play a
role in the pathogenesis of rheumatoid arthritis (RA). The heritability of RA has been …

[PDF][PDF] One year in review: the pathogenesis of rheumatoid arthritis

V Picerno, F Ferro, A Adinolfi, E Valentini… - Clin Exp …, 2015 - clinexprheumatol.org
The pathogenesis of rheumatoid arthritis (RA) is a complex scenario that, to date, is not fully
elucidated. However, scientific progress has enabled us to understand several mechanisms …

[HTML][HTML] Genetics of rheumatoid arthritis susceptibility, severity, and treatment response

S Viatte, A Barton - Seminars in immunopathology, 2017 - Springer
A decade after the first genome-wide association study in rheumatoid arthritis (RA), a
plethora of genetic association studies have been published on RA and its clinical or …

Epigenetics in rheumatoid arthritis

K Klein, S Gay - Current opinion in rheumatology, 2015 - journals.lww.com
Epigenetics in rheumatoid arthritis : Current Opinion in Rheumatology Epigenetics in rheumatoid
arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …

The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts

K Klein, PA Kabala, AM Grabiec, RE Gay… - Annals of the …, 2016 - ard.bmj.com
Objective To investigate the effects of BET bromodomain protein inhibition on inflammatory
activation and functional properties of rheumatoid arthritis synovial fibroblasts (RASF) …

The tumor‐like phenotype of rheumatoid synovium: molecular profiling and prospects for precision medicine

S You, JH Koh, L Leng, WU Kim… - Arthritis & …, 2018 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by destructive
hyperplasia of the synovium. Fibroblast‐like synoviocytes (FLS) are a major component of …

One genome, many cell states: epigenetic control of innate immunity

I Fraschilla, H Amatullah, KL Jeffrey - Current opinion in immunology, 2022 - Elsevier
Highlights•Chromatin dynamics regulate pattern, timing and magnitude of gene
expression.•Signal transduction downstream of TLR4 regulate histones for inducible gene …

Comparison of EMG signals recorded by surface electrodes on endotracheal tube and thyroid cartilage during monitored thyroidectomy

FY Chiang, IC Lu, PY Chang, G Dionigi… - … Kaohsiung journal of …, 2017 - Wiley Online Library
A variety of electromyography (EMG) recording methods were reported during intraoperative
neural monitoring (IONM) of recurrent laryngeal nerve (RLN) in thyroid surgery. This study …

[HTML][HTML] Potential clinical biomarkers in rheumatoid arthritis with an omic approach

Y Puentes-Osorio, P Amariles, MÁ Calleja… - Autoimmunity …, 2021 - Springer
Objective To aid in the selection of the most suitable therapeutic option in patients with
diagnosis of rheumatoid arthritis according to the phase of disease, through the review of …