Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …

COVID-19 infection caused by SARS-CoV-2 is considered catastrophic because it affects
multiple organs, particularly those of the respiratory tract. Although the consequences of this …

Synchrotron X-rays can be used to obtain highly detailed images of parts of the lung.
However, micro-motion artifacts induced by such as cardiac motion impede quantitative …

Background Ventilator-induced lung injury (VILI) is a complex pathophysiological process
leading to acute respiratory distress syndrome (ARDS) and poor outcomes in affected …

Synchrotron radiation offers unique properties of coherence, utilized in phase-contrast
imaging, and high flux as well as a wide energy spectrum which allow the selection of very …

Mechanical ventilation exposes the lung to injurious stresses and strains that can negatively
affect clinical outcomes in acute respiratory distress syndrome or cause pulmonary …

Imaging the internal architecture of fast-vibrating structures at micrometer scale and kilohertz
frequencies poses great challenges for numerous applications, including the study of …

Rationale: Intratidal changes in regional lung aeration, as assessed with dynamic four-
dimensional computed tomography (CT; 4DCT), may indicate the processes of recruitment …

The magnitude and distribution of strain imposed on the peripheral airspaces by mechanical
ventilation at the microscopic level and the consequent deformations are unknown despite …

We present a novel computational model for the dynamics of alveolar recruitment/
derecruitment (RD), which reproduces the underlying characteristics typically observed in …