With aging, the nervous system gradually undergoes degeneration. Increased oxidative
stress, endoplasmic reticulum stress, mitochondrial dysfunction, and cell death are …

Melatonin is the major secretory product synthesized and secreted by the pineal gland and
shows both a wide distribution within phylogenetically distant organisms from bacteria to …

Melatonin is a ubiquitous hormone found in various organisms and highly affects the
function of immune cells. In this review, we summarize the current understanding of the …

Besides its well‐known regulatory role on circadian rhythm, the pineal gland hormone
melatonin has other biological functions and a distinct metabolism in various cell types and …

It is commonly accepted that melatonin (N-acetyl-5-methoxytryptamine), the most relevant
pineal secretory product, has oncostatic properties in a wide variety of tumors and …

BACKGROUND: Mesenchymal stem cells within the stromal-vascular fraction of
subcutaneous adipose tissue, adipose-derived stem cells (ADSCs), produced soluble …

Brain and spinal cord are implicated in incidences of two of the most severe injuries of
central nervous system (CNS). Traumatic brain injury (TBI) is a devastating neurological …

Increasing evidence demonstrates that melatonin has an anti‐apoptotic effect in somatic
cells. However, whether melatonin can protect against germ cell apoptosis remains obscure …

The role of melatonin in the mediation of apoptotic events has recently gained attention,
especially after recent studies have reported that melatonin exerts antiapoptotic actions in …

The potential for human and ecological toxicity associated with nanomaterials is a growing
area of investigation. In mammalian cells, nanoparticles have been shown to induce …