Crystallography of nanocrystalline materials has witnessed a true revolution in the past 10
years, thanks to the introduction of protocols for 3D acquisition and analysis of electron …

In 2013 we established a cryo-electron microscopy (cryo-EM) technique called microcrystal
electron diffraction (MicroED). Since that time, data collection and analysis schemes have …

MyD88 and MAL are Toll-like receptor (TLR) adaptors that signal to induce pro-inflammatory
cytokine production. We previously observed that the TIR domain of MAL (MALTIR) forms …

Single-crystal electron diffraction (SCED) is emerging as an effective technique to determine
and refine the structures of unknown nano-sized crystals. In this work, the implementation of …

Serial X-ray crystallography at free-electron lasers allows to solve biomolecular structures
from sub-micron-sized crystals. However, beam time at these facilities is scarce, and …

Structures of two globular proteins were determined ab initio using microcrystal electron
diffraction (MicroED) data that were collected on a direct electron detector in counting mode …

Electron diffraction is a relatively novel alternative to X-ray crystallography for the structure
determination of macromolecules from three-dimensional nanometre-sized crystals. The …

3D electron diffraction is an emerging technique for the structural analysis of nanocrystals.
The challenges that 3D electron diffraction has to face for providing reliable data for structure …

Electron crystallography has a storied history which rivals that of its more established X-ray-
enabled counterpart. Recent advances in data collection and analysis have sparked a …

Serial rotation electron diffraction (SerialRED) has been developed as a fully automated
technique for three-dimensional electron diffraction data collection that can run …