Vascular endothelial growth factor: a neurovascular target in neurological diseases

C Lange, E Storkebaum, CR De Almodóvar… - Nature Reviews …, 2016 - nature.com
Brain function critically relies on blood vessels to supply oxygen and nutrients, to establish a
barrier for neurotoxic substances, and to clear waste products. The archetypal vascular …

The role of fibroblast growth factor (FGF) signaling in tissue repair and regeneration

M Farooq, AW Khan, MS Kim, S Choi - Cells, 2021 - mdpi.com
Fibroblast growth factors (FGFs) are a large family of secretory molecules that act through
tyrosine kinase receptors known as FGF receptors. They play crucial roles in a wide variety …

Phylogenetic evidence for the modular evolution of metazoan signalling pathways

LS Babonis, MQ Martindale - … Transactions of the …, 2017 - royalsocietypublishing.org
Communication among cells was paramount to the evolutionary increase in cell type
diversity and, ultimately, the origin of large body size. Across the diversity of Metazoa, there …

[HTML][HTML] Molecular mechanisms underlying variations in lung function: a systems genetics analysis

M Obeidat, K Hao, Y Bossé, DC Nickle… - The Lancet …, 2015 - thelancet.com
Background Lung function measures reflect the physiological state of the lung, and are
essential to the diagnosis of chronic obstructive pulmonary disease (COPD). The SpiroMeta …

Vascular endothelial growth factor 165-binding heparan sulfate promotes functional recovery from cerebral ischemia

SJ Chan, E Esposito, K Hayakawa, E Mandaville… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Although VEGF165 (vascular endothelial growth factor-165) is
able to enhance both angiogenesis and neurogenesis, it also increases vascular …

Possible cooption of a VEGF-driven tubulogenesis program for biomineralization in echinoderms

M Morgulis, T Gildor, M Roopin… - Proceedings of the …, 2019 - National Acad Sciences
Biomineralization is the process by which living organisms use minerals to form hard
structures that protect and support them. Biomineralization is believed to have evolved …

Cellular and Molecular Mechanisms of Hydra Regeneration

PC Reddy, A Gungi, M Unni - Evo-Devo: Non-model Species in Cell and …, 2019 - Springer
Regeneration of lost body parts is essential to regain the fitness of the organism for
successful living. In the animal kingdom, organisms from different clades exhibit varied …

VEGF receptor tyrosine kinases: key regulators of vascular function

A Álvarez-Aznar, L Muhl, K Gaengel - Current topics in developmental …, 2017 - Elsevier
Vascular endothelial growth factor receptor (VEGFR) tyrosine kinases are key regulators of
vascular development in vertebrates. Their activation is regulated through a family of …

Wound‐induced cell proliferation during animal regeneration

L Ricci, M Srivastava - Wiley Interdisciplinary Reviews …, 2018 - Wiley Online Library
Many animal species are capable of replacing missing tissues that are lost upon injury or
amputation through the process of regeneration. Although the extent of regeneration is …

Genome-wide survey of single-nucleotide polymorphisms reveals fine-scale population structure and signs of selection in the threatened Caribbean elkhorn coral …

MK Devlin-Durante, IB Baums - PeerJ, 2017 - peerj.com
The advent of next-generation sequencing tools has made it possible to conduct fine-scale
surveys of population differentiation and genome-wide scans for signatures of selection in …