Promoting safe and effective use of aerosol devices in COVID-19: risks and suggestions for viral transmission

A Ari - Expert Opinion on Drug Delivery, 2020 - Taylor & Francis
While aerosol devices play a crucial role in the treatment of pulmonary diseases, aerosol
drug delivery is considered as a risk for viral transmission and cross-infection between …

Aerosol delivery through high-flow nasal therapy: Technical issues and clinical benefits

C Calabrese, A Annunziata, DF Mariniello… - Frontiers in …, 2023 - frontiersin.org
High-flow nasal cannula (HFNC) therapy is an oxygen delivery method particularly used in
patients affected by hypoxemic respiratory failure. In comparison with the conventional “low …

Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support

J Li, K Liu, S Lyu, G Jing, B Dai, R Dhand, HL Lin… - Annals of intensive …, 2023 - Springer
Background Clinical practice of aerosol delivery in conjunction with respiratory support
devices for critically ill adult patients remains a topic of controversy due to the complexity of …

The influence of changing interfaces on aerosol delivery within high flow oxygen setting in adults: an in-vitro study

YM Madney, NI Laz, AA Elberry, H Rabea… - Journal of Drug Delivery …, 2020 - Elsevier
Despite the fact that the nasal-cannula is more comfortable than facemask, using facemask
with high flow oxygen therapy (HFOT) may be beneficial in mouth-breathers. The aim of the …

Aerosol delivery through an adult high-flow nasal cannula circuit using low-flow oxygen

YM Madney, M Fathy, AA Elberry, H Rabea… - Respiratory …, 2019 - rc.rcjournal.com
BACKGROUND: There has been a growing trend toward delivering aerosolized medications
using high-flow nasal cannula (HFNC). In some cases, patients who do not require high-flow …

Effects of fill volume and humidification on aerosol delivery during single-limb noninvasive ventilation

H Saeed, M Mohsen, AS Eldin, AA Elberry… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: The aim of this work was to determine the effect of fill volume and
humidification change on aerosol delivery during single-limb noninvasive ventilation (NIV) …

Investigation of fugitive aerosols released into the environment during high-flow therapy

JA McGrath, C O'Toole, G Bennett, M Joyce, MA Byrne… - Pharmaceutics, 2019 - mdpi.com
Background: Nebulised medical aerosols are designed to deliver drugs to the lungs to aid in
the treatment of respiratory diseases. However, an unintended consequence is the potential …

Modeling and optimization of nebulizers' performance in non-invasive ventilation using different fill volumes: comparative study between vibrating mesh and jet …

H Saeed, AMA Ali, AA Elberry, AS Eldin… - Pulmonary …, 2018 - Elsevier
Backgrounds Substituting nebulisers by another, especially in non-invasive ventilation (NIV),
involves many process-variables, eg nebulizer-type and fill-volume of respirable-dose …

Lung deposition and systemic bioavailability of different aerosol devices with and without humidification in mechanically ventilated patients

IOF Moustafa, MRAA Ali, M Al Hallag, H Rabea, JB Fink… - Heart & Lung, 2017 - Elsevier
Background During mechanical ventilation medical aerosol delivery has been reported to be
upto two fold greater with dry inhaled gas than with heated humidity. Urine levels at 0.5 h …

Performance of large spacer versus nebulizer T-piece in single-limb noninvasive ventilation

HS Harb, AA Elberry, H Rabea, M Fathy… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: Predosing patients with COPD with salbutamol by using a pressurized
metered-dose-inhaler (pMDI) as a bronchodilator was hypothesized to improve the …