[HTML][HTML] Development of a neonatal Göttingen Minipig model for dose precision in perinatal asphyxia: technical opportunities, challenges, and potential further steps
MS Stroe, L Van Bockstal, A Valenzuela… - Frontiers in …, 2023 - frontiersin.org
Animal models provide useful information on mechanisms in human disease conditions, but
also on exploring (patho) physiological factors affecting pharmacokinetics, safety, and …
also on exploring (patho) physiological factors affecting pharmacokinetics, safety, and …
Rate-and Region-Dependent Mechanical Properties of Göttingen Minipig Brain Tissue in Simple Shear and Unconfined Compression
Traumatic brain injury (TBI), particularly from explosive blasts, is a major cause of casualties
in modern military conflicts. Computational models are an important tool in understanding …
in modern military conflicts. Computational models are an important tool in understanding …
Strain-induced collagen denaturation is rate dependent in failure of cerebral arteries
While soft tissues are commonly damaged by mechanical loading, the manifestation of this
damage at the microstructural level is not fully understood. Specifically, while rate-induced …
damage at the microstructural level is not fully understood. Specifically, while rate-induced …
Dynamic cerebral autoregulation is governed by two time constants: Arterial transit time and feedback time constant
SJ Payne - The Journal of Physiology, 2024 - Wiley Online Library
Dynamic cerebral autoregulation (dCA) is the mechanism that describes how the brain
maintains cerebral blood flow approximately constant in response to short‐term changes in …
maintains cerebral blood flow approximately constant in response to short‐term changes in …
Integrated approaches in pediatric pharmacotherapy: the neonatal Göttingen minipig model for drug disposition in perinatal asphyxia and therapeutic hypothermia
MS Stroe - 2024 - repository.uantwerpen.be
Pediatric drug therapy presents challenges due to the pronounced growth and development
during early life stages, affecting drug response. Perinatal asphyxia (PA) is a condition in …
during early life stages, affecting drug response. Perinatal asphyxia (PA) is a condition in …