Machine learning in quantitative PET: A review of attenuation correction and low-count image reconstruction methods

T Wang, Y Lei, Y Fu, WJ Curran, T Liu, JA Nye, X Yang - Physica Medica, 2020 - Elsevier
The rapid expansion of machine learning is offering a new wave of opportunities for nuclear
medicine. This paper reviews applications of machine learning for the study of attenuation …

[HTML][HTML] Imaging of T-cells and their responses during anti-cancer immunotherapy

M Krekorian, GO Fruhwirth, M Srinivas, CG Figdor… - Theranostics, 2019 - ncbi.nlm.nih.gov
Imaging of T-cells and their responses during anti-cancer immunotherapy - PMC Back to Top
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

PD-L1 PET/CT Imaging with Radiolabeled Durvalumab in Patients with Advanced-Stage Non–Small Cell Lung Cancer

J Smit, FJ Borm, ALN Niemeijer… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Better biomarkers are needed to predict treatment outcome in non–small cell lung cancer
(NSCLC) patients treated with anti–programmed death-1/programmed death-ligand 1 (PD …

Programmed cell death-1/ligand-1 PET imaging: a novel tool to optimize immunotherapy?

SR Verhoeff, MM van den Heuvel, CML van Herpen… - PET clinics, 2020 - pet.theclinics.com
Immune checkpoint inhibitors (ICIs) targeting the programmed cell death (ligand)-1 (PD-[L]
1) axis have emerged at the forefront of cancer treatment. 1 Numerous ICIs have received …

90Y radioembolization in the treatment of neuroendocrine neoplasms: results of an international multicenter retrospective study

BM Schaarschmidt, M Wildgruber… - Journal of Nuclear …, 2022 - Soc Nuclear Med
In neuroendocrine neoplasms (NENs), the presence of distant metastases has a severe
impact on survival leading to a relevant decrease in the 5-y survival rate. Here, 90Y …

Response prediction and evaluation using PET in patients with solid tumors treated with immunotherapy

FJ Borm, J Smit, DE Oprea-Lager, M Wondergem… - Cancers, 2021 - mdpi.com
Simple Summary In cancer treatment, immunotherapy is increasingly becoming important as
a component of first-line treatment and has improved the prognosis of patients since its …

Advances and challenges in immunoPET methodology

P Mohr, J van Sluis, MN Lub-de Hooge… - Frontiers in Nuclear …, 2024 - frontiersin.org
Immuno-positron emission tomography (immunoPET) enables imaging of specific targets
that play a role in targeted therapy and immunotherapy, such as antigens on cell …

Optimal imaging time points considering accuracy and precision of Patlak linearization for 89Zr-immuno-PET: a simulation study

JE Wijngaarden, MC Huisman, JEE Pouw… - EJNMMI research, 2022 - Springer
Abstract Purpose Zirconium-89-immuno-positron emission tomography (89Zr-immuno-PET)
has enabled visualization of zirconium-89 labelled monoclonal antibody (89Zr-mAb) uptake …

The development process of 'fit-for-purpose'imaging biomarkers to characterize the tumor microenvironment

JJ Eertink, I Bahce, JC Waterton, MC Huisman… - Frontiers in …, 2024 - frontiersin.org
Immune-based treatment approaches are successfully used for the treatment of patients with
cancer. While such therapies can be highly effective, many patients fail to benefit. To provide …

Sensitivity of 18F-fluorodihydrotestosterone PET-CT to count statistics and reconstruction protocol in metastatic castration-resistant prostate cancer

MCF Cysouw, GM Kramer, D Heijtel, RC Schuit… - EJNMMI research, 2019 - Springer
Abstract Objectives Whole body [18 F]-fluorodihydrotestosterone positron emission
tomography ([18 F] FDHT PET) imaging directly targets the androgen receptor and is a …