Growth differentiation factor 11: A new hope for the treatment of cardiovascular diseases

Y Shao, Y Wang, J Xu, Y Yuan, D Xing - Cytokine & Growth Factor Reviews, 2023 - Elsevier
ABSTRACT Growth differentiation factor 11 (GDF11) is a member of the transforming growth
factor-β superfamily that has garnered significant attention due to its anti-cardiac aging …

Progress in the relationship between GDF11 and depression

X Jin, W Guan - Life Sciences, 2024 - Elsevier
Annually, the frequency of morbidity in depression has increased progressively in response
to life stressors, and there is an increasing trend toward younger morbidity. The …

A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels

J Zhou, C Cattoglio, Y Shao, HP Tirumala… - Genes & …, 2023 - genesdev.cshlp.org
Loss-of-function mutations in MECP2 cause Rett syndrome (RTT), a severe neurological
disorder that mainly affects girls. Mutations in MECP2 do occur in males occasionally and …

Evidence Synthesis of Gene Therapy and Gene Editing from Different Disorders—Implications for Individuals with Rett Syndrome: A Systematic Review

J Singh, E Goodman-Vincent, P Santosh - International Journal of …, 2023 - mdpi.com
This systematic review and thematic analysis critically evaluated gene therapy trials in
amyotrophic lateral sclerosis, haemoglobinopathies, immunodeficiencies, leukodystrophies …

MeCP2 Interacts with the Super Elongation Complex to Regulate Transcription

JY Sonn, W Kim, M Iwanaszko, Y Aoi, Y Li, L Parkitny… - bioRxiv, 2024 - biorxiv.org
Loss-of-function mutations in methyl-CpG binding protein 2 (MECP2) cause Rett syndrome,
a postnatal neurodevelopmental disorder that occurs in~ 1/10,000 live female births. MeCP2 …