Cell viability is defined as the number of healthy cells in a sample and proliferation of cells is
a vital indicator for understanding the mechanisms in action of certain genes, proteins and …

The proliferative activity of tumour cells represents an important prognostic marker in the
diagnosis of cancer. One of the methods for assessing the proliferative activity of cells is the …

The cell proliferation antigen Ki-67 is widely used in cancer histopathology, but estimations
of Ki-67 expression levels are inconsistent and understanding of its regulation is limited …

The leading parameters that define treatment recommendations in early breast cancer are
oestrogen-receptor, progesterone-receptor, and human epidermal growth-factor status …

The capacity of immunity to control and shape cancer, that is, cancer immunoediting, is the
result of three processes,,,,,,, that function either independently or in sequence: elimination …

Abstract Bee venom (BV)(api-toxin) has been widely used in the treatment of some immune-
related diseases, as well as in recent times in treatment of tumors. Several cancer cells …

Bromodeoxyuridine (BrdU) is a thymidine analog that incorporates DNA of dividing cells
during the S-phase of the cell cycle. As such, BrdU is used for birth dating and monitoring …

What do we know about Ki-67, apart from its usefulness as a cell proliferation biomarker in
histopathology? Discovered in 1983, the protein and its regulation of expression and …

Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating
cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review …

Constitutive heterochromatin is typically defined by high levels of DNA methylation and H3
lysine 9 trimethylation (H3K9Me3), whereas facultative heterochromatin displays DNA …