Scientific interest in serotonergic psychedelics (eg, psilocybin and LSD; 5‐HT2A receptor
agonists) has dramatically increased within the last decade. Clinical studies administering …

This work provides an overview of the most consistent alterations in bipolar disorder (BD),
attempting to unify them in an internally coherent working model of the pathophysiology of …

The intricate processes of microbiota-gut-brain communication in modulating human
cognition and emotion, especially in the context of mood disorders, have remained elusive …

Background Bipolar disorder (BD) has been linked to abnormalities in the communication
and gray matter volume (GMV) of large-scale brain networks, as reflected by impaired …

Background Bipolar disorder (BD) is a mental disorder characterized by mood fluctuations
between an acute episodic state of either mania or depression and a clinically remitted state …

Dysfunction of the striatum is frequently associated with sleep disturbances. However, its
role in sleep-wake regulation has been paid little attention even though the striatum densely …

How phenomenal experience and behavior are related to neural activity in physiology and
psychopathology represents a fundamental question in neuroscience and psychiatry. The …

Alterations in activity and connectivity of brain circuits implicated in emotion processing and
emotion regulation have been observed during resting-state for different clinical phases of …

Objective Abnormalities in spontaneous brain activity, measured with resting-state functional
magnetic resonance imaging (rs-fMRI), may be key biomarkers for bipolar disorders. This …

Evidence has indicated abnormalities of thalamo-cortical functional connectivity (FC) in
bipolar disorder during a depressive episode (BDD) and major depressive disorder (MDD) …