Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

The history of H 2 S–as an environmental toxin–dates back to 1700, to the observations of
the Italian physician Bernardino Ramazzini, whose book “De Morbis Artificum Diatriba” …

Diabetic kidney disease is known as a major cause of chronic kidney disease and end stage
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …

Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the
globe and is one of the main complications in patients with type 1 and 2 diabetes. The …

The influence of hyperhomocysteinemia (HHCy) on cardiovascular disease (CVD) remains
unclear. HHCy is associated with inflammation and atherosclerosis, and it is an independent …

Sulphurous mineral waters have been traditionally used in medical hydrology as treatment
for skin, respiratory, and musculoskeletal disorders. However, driven by recent intense …

Diabetic kidney disease develops in approximately 40% of diabetic patients and is a major
cause of chronic kidney diseases (CKD) and end stage kidney disease (ESKD) worldwide …

Reactive sulfur species (RSS) have been recognized in the last two decades as very
important molecules in redox regulation. They are involved in metabolic processes and, in …

Background and Purpose Hydrogen sulfide (H2S) is a gaseous signal molecule with
antioxidative properties. Sirtuin 3 (SIRT3) is closely associated with mitochondrial function …

Diabetes is one of the most prevalent metabolic disorders and is estimated to affect 400
million of 4.4% of population worldwide in the next 20 year. In diabetes, risk to develop …