Pulsatile blood flow through the cavities of the heart and great vessels is time-varying and
multidirectional. Access to all regions, phases and directions of cardiovascular flows has …

Aortic valve stenosis (AS) is the most prevalent valvular heart disease in developed
countries and is associated with the development of severe secondary complications such …

Background: Suspected genetic causes for extracellular matrix (ECM) dysregulation in the
ascending aorta in patients with bicuspid aortic valves (BAV) have influenced strategies and …

Background In patients with bicuspid valve (BAV), ascending aorta (AAo) dilatation may be
caused by altered flow patterns and wall shear stress (WSS). These differences may explain …

Background Wall shear stress (WSS) is a stimulus for vessel wall remodeling. Differences in
ascending aorta (AA o) hemodynamics have been reported between bicuspid aortic valve …

Objectives The aim of this study was to evaluate the role of wall shear stress (WSS) as a
predictor of ascending aorta (AAo) growth at 5 years or greater follow-up. Background Aortic …

Magnetic resonance imaging (MRI) has become an important tool for the clinical evaluation
of patients with cardiac and vascular diseases. Since its introduction in the late 1980s …

Magnetic resonance imaging (MRI) techniques provide non-invasive and non-ionising
methods for the highly accurate anatomical depiction of the heart and vessels throughout the …

Advances in the diagnosis and management of congenital heart disease (CHD) have
resulted in a growing population of patients surviving well into adulthood and requiring …

Purpose To investigate the reproducibility and interobserver variability of 3D aortic velocity
vector fields and wall shear stress (WSS) averaged over five systolic timeframes derived …