Peering into tunneling nanotubes—The path forward
D Cordero Cervantes, C Zurzolo - The EMBO journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …
Wiring through tunneling nanotubes–from electrical signals to organelle transfer
S Abounit, C Zurzolo - Journal of cell science, 2012 - journals.biologists.com
Tunneling nanotubes (TNTs) represent a subset of F-actin-based transient tubular
connections that allow direct communication between distant cells. Recent studies have …
connections that allow direct communication between distant cells. Recent studies have …
Intercellular nanotubes mediate mitochondrial trafficking between cancer and immune cells
Cancer progresses by evading the immune system. Elucidating diverse immune evasion
strategies is a critical step in the search for next-generation immunotherapies for cancer …
strategies is a critical step in the search for next-generation immunotherapies for cancer …
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
H Scheiblich, C Dansokho, D Mercan, SV Schmidt… - Cell, 2021 - cell.com
Microglia are the CNS resident immune cells that react to misfolded proteins through pattern
recognition receptor ligation and activation of inflammatory pathways. Here, we studied how …
recognition receptor ligation and activation of inflammatory pathways. Here, we studied how …
Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells
X Wang, HH Gerdes - Cell Death & Differentiation, 2015 - nature.com
Tunneling nanotubes (TNTs) are F-actin-based membrane tubes that form between cells in
culture and in tissues. They mediate intercellular communication ranging from electrical …
culture and in tissues. They mediate intercellular communication ranging from electrical …
Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance
Our vision of cancer has changed during the past decades. Indeed tumors are now
perceived as complex entities where tumoral and stromal components interact closely …
perceived as complex entities where tumoral and stromal components interact closely …
Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma
E Lou, S Fujisawa, A Morozov, A Barlas, Y Romin… - PloS one, 2012 - journals.plos.org
Tunneling nanotubes are long, non-adherent F-actin-based cytoplasmic extensions which
connect proximal or distant cells and facilitate intercellular transfer. The identification of …
connect proximal or distant cells and facilitate intercellular transfer. The identification of …
Melatonin reshapes the mitochondrial network and promotes intercellular mitochondrial transfer via tunneling nanotubes after ischemic‐like injury in hippocampal …
Mitochondrial dysfunction is considered one of the hallmarks of ischemia/reperfusion injury.
Mitochondria are plastic organelles that undergo continuous biogenesis, fusion, and fission …
Mitochondria are plastic organelles that undergo continuous biogenesis, fusion, and fission …
Role of connexin 43 in different forms of intercellular communication–gap junctions, extracellular vesicles and tunnelling nanotubes
TM Ribeiro-Rodrigues… - Journal of cell …, 2017 - journals.biologists.com
Communication is important to ensure the correct and efficient flow of information, which is
required to sustain active social networks. A fine-tuned communication between cells is vital …
required to sustain active social networks. A fine-tuned communication between cells is vital …
Tunneling nanotubes, TNT, communicate glioblastoma with surrounding non-tumor astrocytes to adapt them to hypoxic and metabolic tumor conditions
S Valdebenito, S Malik, R Luu, O Loudig, M Mitchell… - Scientific reports, 2021 - nature.com
Cell-to-cell communication is essential for the development and proper function of
multicellular systems. We and others demonstrated that tunneling nanotubes (TNT) …
multicellular systems. We and others demonstrated that tunneling nanotubes (TNT) …