Acute kidney injury in the critically ill: an updated review on pathophysiology and management

P Pickkers, M Darmon, E Hoste, M Joannidis… - Intensive care …, 2021 - Springer
Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only
affects acute morbidity and mortality, but also a patient's long-term prognosis. In this …

[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

[HTML][HTML] Sepsis—pathophysiology and therapeutic concepts

D Jarczak, S Kluge, A Nierhaus - Frontiers in medicine, 2021 - frontiersin.org
Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

Biomarkers in acute kidney injury–pathophysiological basis and clinical performance

EV Schrezenmeier, J Barasch, K Budde… - Acta …, 2017 - Wiley Online Library
Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …

Biomarkers of acute kidney injury: the pathway from discovery to clinical adoption

K Kashani, W Cheungpasitporn… - Clinical Chemistry and …, 2017 - degruyter.com
Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …

Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis

HC Pan, SY Yang, TTY Chiou, CC Shiao, CH Wu… - Critical Care, 2022 - Springer
Background Several biomarkers have been proposed to predict the occurrence of acute
kidney injury (AKI); however, their efficacy varies between different trials. The aim of this …

Neutrophil gelatinase-associated lipocalin measured on clinical laboratory platforms for the prediction of acute kidney injury and the associated need for dialysis …

C Albert, A Zapf, M Haase, C Röver… - American Journal of …, 2020 - Elsevier
Rationale & Objective The usefulness of measures of neutrophil gelatinase-associated
lipocalin (NGAL) in urine or plasma obtained on clinical laboratory platforms for predicting …

Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis

SJ Klein, AK Brandtner, GF Lehner, H Ulmer… - Intensive care …, 2018 - Springer
Purpose Acute kidney injury (AKI) frequently occurs in critically ill patients and often
precipitates use of renal replacement therapy (RRT). However, the ideal circumstances for …

Cardio-pulmonary-renal interactions: a multidisciplinary approach

F Husain-Syed, PA McCullough, HW Birk… - Journal of the American …, 2015 - jacc.org
Over the past decade, science has greatly advanced our understanding of interdependent
feedback mechanisms involving the heart, lung, and kidney. Organ injury is the …

Clinical use of the urine biomarker [TIMP-2]×[IGFBP7] for acute kidney injury risk assessment

A Vijayan, S Faubel, DJ Askenazi, J Cerda… - American Journal of …, 2016 - Elsevier
Acute kidney injury (AKI) is a serious complication, commonly occurring in the critically ill
population, with devastating short-and long-term consequences. Despite standardization of …