Overview of the 2022 WHO classification of neuroendocrine neoplasms
In this review, we detail the changes and the relevant features that are applied to
neuroendocrine neoplasms (NENs) in the 2022 WHO Classification of Endocrine and …
neuroendocrine neoplasms (NENs) in the 2022 WHO Classification of Endocrine and …
Updates in histopathological classification and tissue biomarkers of digestive neuroendocrine neoplasms: What the clinician should know
A Couvelard, A Cazes, J Cros - Best Practice & Research Clinical …, 2023 - Elsevier
Histopathological classifications of neuroendocrine neoplasms (NEN) change regularly and
the latest WHO classification published in 2022, which concerns all NEN in the body …
the latest WHO classification published in 2022, which concerns all NEN in the body …
A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution
Bulk-tissue DNA methylomes represent an average over many different cell types,
hampering our understanding of cell-type-specific contributions to disease development. As …
hampering our understanding of cell-type-specific contributions to disease development. As …
Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 …
WM Hackeng, LAA Brosens, JY Kim, R O'Sullivan… - Gut, 2022 - gut.bmj.com
Objective Recent studies have found aristaless-related homeobox gene (ARX)/pancreatic
and duodenal homeobox 1 (PDX1), alpha-thalassemia/mental retardation X-linked …
and duodenal homeobox 1 (PDX1), alpha-thalassemia/mental retardation X-linked …
Survival and incidence patterns of pancreatic neuroendocrine tumors over the last 2 decades: a SEER database analysis
Background Pancreatic neuroendocrine tumors (pNETs) are rare cancers with outcomes
determined by multiple factors including grade, stage, and clinical presentation. In this study …
determined by multiple factors including grade, stage, and clinical presentation. In this study …
[HTML][HTML] Gastrinoma
RT Jensen, T Ito - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …
Neuroendocrine neoplasms of the pancreas: diagnosis and pitfalls
B Konukiewitz, M Jesinghaus, A Kasajima, G Klöppel - Virchows Archiv, 2022 - Springer
Common to neuroendocrine neoplasms of the pancreas is their expression of
synaptophysin, chromogranin A, and/or INSM1. They differ, however, in their histological …
synaptophysin, chromogranin A, and/or INSM1. They differ, however, in their histological …
DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association
Here we report the DNA methylation profile of 84 sporadic pancreatic neuroendocrine
tumors (PanNETs) with associated clinical and genomic information. We identified three …
tumors (PanNETs) with associated clinical and genomic information. We identified three …
Treatment of advanced gastroenteropancreatic neuroendocrine neoplasia, are we on the way to personalised medicine?
A Rinke, CJ Auernhammer, L Bodei, M Kidd, S Krug… - Gut, 2021 - gut.bmj.com
Gastroenteropancreatic neuroendocrine neoplasia (GEPNEN) comprises clinically as well
as prognostically diverse tumour entities often diagnosed at late stage. Current classification …
as prognostically diverse tumour entities often diagnosed at late stage. Current classification …
Challenges and perspectives in computational deconvolution of genomics data
Deciphering cell-type heterogeneity is crucial for systematically understanding tissue
homeostasis and its dysregulation in diseases. Computational deconvolution is an efficient …
homeostasis and its dysregulation in diseases. Computational deconvolution is an efficient …