Self-Adjuvanting TLR7/8 Agonist and Fentanyl Hapten Co-Conjugate Achieves Enhanced Protection against Fentanyl Challenge

N Powers, C Massena, B Crouse, M Smith… - Bioconjugate …, 2023 - ACS Publications
Currently approved pharmacotherapies for opioid use disorders (OUDs) and overdose
reversal agents are insufficient to slow the spread of OUDs due to the proliferation of …

[HTML][HTML] Vaccines to Treat Substance Use Disorders: Current Status and Future Directions

T Lu, X Li, W Zheng, C Kuang, B Wu, X Liu, Y Xue… - Pharmaceutics, 2024 - mdpi.com
Addiction, particularly in relation to psychostimulants and opioids, persists as a global health
crisis with profound social and economic ramifications. Traditional interventions, including …

Multivalent Vaccination Strategies Protect against Exposure to Polydrug Opioid and Stimulant Mixtures in Mice and Rats

D Song, B Crouse, J Vigliaturo, MM Wu… - ACS Pharmacology & …, 2023 - ACS Publications
Illicit drug mixtures containing opioids and stimulants have been responsible for the majority
of fatal drug overdoses among occasional users, and those with either opioid use disorder …