P-Stereogenic phosphorus ligands in asymmetric catalysis

T Imamoto - Chemical reviews, 2024 - ACS Publications
Chiral phosphorus ligands play a crucial role in asymmetric catalysis for the efficient
synthesis of useful optically active compounds. They are largely categorized into two …

Recent advances in the enantioselective synthesis of chiral amines via transition metal-catalyzed asymmetric hydrogenation

A Cabré, X Verdaguer, A Riera - Chemical Reviews, 2021 - ACS Publications
Chiral amines are key structural motifs present in a wide variety of natural products, drugs,
and other biologically active compounds. During the past decade, significant advances have …

Rigid P-Chiral Phosphine Ligands with tert-Butylmethylphosphino Groups for Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes

T Imamoto, K Tamura, Z Zhang, Y Horiuchi… - Journal of the …, 2012 - ACS Publications
Both enantiomers of 2, 3-bis (tert-butylmethylphosphino) quinoxaline (QuinoxP*), 1, 2-bis
(tert-butylmethylphosphino) benzene (BenzP*), and 1, 2-bis (tert-butylmethylphosphino)-4, 5 …

Searching for Practically Useful P‐Chirogenic Phosphine Ligands

T Imamoto - The Chemical Record, 2016 - Wiley Online Library
In this account, the design, synthesis, and application of P‐chirogenic phosphine ligands
that have been mainly carried out in our laboratory over the last three decades are …

Light-Driven N-Heterocyclic Carbene-Catalyzed Multi-Component Reaction for the Synthesis of β-Amino Ketones

C Shi, N Zhong, L Guo, J Yin, C Yang, W Xia - Organic Letters, 2024 - ACS Publications
A N-heterocyclic carbene-catalyzed (NHC) three-component reaction involving N-
aminopyridinium salts, alkenes, and aldehydes for the synthesis of β-amino ketones is …

Synthesis of chiral aliphatic amines through asymmetric hydrogenation.

TL Liu, CJ Wang, X Zhang - Angewandte Chemie, 2013 - search.ebscohost.com
Chiral amines and their derivates are important building blocks for the synthesis of many
pharmaceutical and biologically active molecules.[1] Methods for preparing chiral aromatic …

MaxPHOS Ligand: PH/NH Tautomerism and Rhodium‐Catalyzed Asymmetric Hydrogenations

E Cristóbal‐Lecina, P Etayo, S Doran… - … synthesis & catalysis, 2014 - Wiley Online Library
MaxPHOS is an active and robust P‐stereogenic ligand for asymmetric catalysis. The
presence of an NH bridge between the two phosphine moieties allows the NH/PH …

Photoredox-mediated N-centered radical addition/semipinacol rearrangement for the convenient synthesis of β-amino (spiro) cyclic ketones

TC Ma, S Yao, MM Qiao, F Yuan, DQ Shi… - Organic Chemistry …, 2021 - pubs.rsc.org
A visible light photoredox-catalyzed N-centered radical addition/semipinacol rearrangement
cascade of cycloalkanol-substituted 1H-indenes or styrenes with N-arylsulfonyl protected 1 …

1, 2-Amidoarylcarbonylation of Styrenes to Access β-Acylamino Ketones by NHC-Catalyzed Radical Relay

D Yin, L Lu, Y Jiang, Y Dou, MC Fu… - The Journal of Organic …, 2024 - ACS Publications
An amidoarylcarbonylation reaction of aromatic aldehydes and olefins with Katritzky
pyridinium salts by N-heterocyclic carbene (NHC)-catalyzed radical relay to construct C–C …

Rhodium‐Catalyzed Highly Regio‐and Enantioselective Hydrogenation of Tetrasubstituted Allenyl Sulfones: An Efficient Access to Chiral Allylic Sulfones

J Long, L Shi, X Li, H Lv, X Zhang - Angewandte Chemie, 2018 - Wiley Online Library
A highly regio‐and enantioselective hydrogenation of challenging tetrasubstituted allenyl
sulfones has been developed, affording chiral allylic sulfones in good yields with excellent …