Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT

X Zhang, B Sai, F Wang, L Wang, Y Wang, L Zheng… - Molecular cancer, 2019 - Springer
Background Metastasis is the main cause of lung cancer mortality. Bone marrow-derived
mesenchymal stem cells (BMSCs) are a component of the cancer microenvironment and …

Circulating exosomal miRNAs as biomarkers for the diagnosis and prognosis of colorectal cancer

K Alves dos Santos, IC Clemente dos Santos… - International journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is one of the most common malignant tumors in the gastrointestinal
tract. It is a multifactorial disease that involves environmental factors, genetic factors, and …

A highly efficient method for isolating urinary exosomes

L He, D Zhu, J Wang, X Wu - … Journal of Molecular …, 2019 - spandidos-publications.com
In the present study, a highly efficient method, referred to as optimized ultrafiltration (OUF),
was developed. This method is effective for exosome purification and also facilitates clinical …

Differentially expressed microRNAs in exosomes of patients with breast cancer revealed by next‑generation sequencing

H Wu, Q Wang, H Zhong, L Li, Q Zhang… - Oncology …, 2020 - spandidos-publications.com
MicroRNAs (miRNAs/miRs) in exosomes play crucial roles in the onset, progression and
metastasis of cancer by regulating the stability of target mRNAs or by inhibiting translation. In …

microRNA‐128‐3p overexpression inhibits breast cancer stem cell characteristics through suppression of Wnt signalling pathway by down‐regulating NEK2

Y Chen, N Wu, L Liu, H Dong… - Journal of Cellular and …, 2020 - Wiley Online Library
Emerging evidence has reported that dysregulation of microRNAs (miRNAs) participated in
the development of diverse types of cancers. Our initial microarray‐based analysis identified …

Circulating non-coding RNA-biomarker potential in neoadjuvant chemotherapy of triple negative breast cancer?

A Ritter, M Hirschfeld, K Berner… - International …, 2019 - spandidos-publications.com
Due to the positive association between neoadjuvant chemotherapy (NACT) and the
promising early response rates of patients with triple negative breast cancer (TNBC) …

Identification of cell‐free circulating MicroRNAs for the detection of early breast cancer and molecular subtyping

KCB Souza, AF Evangelista, LF Leal… - Journal of …, 2019 - Wiley Online Library
Early detection is crucial for achieving a reduction in breast cancer mortality. Analysis of
circulating cell‐free microRNAs present in the serum of cancer patients has emerged as a …

miR‐548c‐5p inhibits colorectal cancer cell proliferation by targeting PGK1

J Ge, J Li, S Na, P Wang, G Zhao… - Journal of cellular …, 2019 - Wiley Online Library
Accumulating studies have implicated that microRNAs (miRNAs) are involved in the
pathogenesis of colorectal cancer (CRC). However, the role of miR‐548c‐5p, a novel …

Hsa-miR-210-3p expression in breast cancer and its putative association with worse outcome in patients treated with Docetaxel

B Pasculli, R Barbano, M Rendina, A Fontana… - Scientific reports, 2019 - nature.com
Abstract MicroRNA-210-3p is the most prominent hypoxia regulated microRNA, and it has
been found significantly overexpressed in different human cancers. We performed the …

Prognostic and Predictive Biomarkers in Familial Breast Cancer

S Deb, A Chakrabarti, SB Fox - Cancers, 2023 - mdpi.com
Simple Summary The importance of identifying and targeting in treating familial breast
cancers is becoming increasingly recognized, in particular with increased availability of …