The oncogene ERG: a key factor in prostate cancer
P Adamo, MR Ladomery - Oncogene, 2016 - nature.com
ETS-related gene (ERG) is a member of the E-26 transformation-specific (ETS) family of
transcription factors with roles in development that include vasculogenesis, angiogenesis …
transcription factors with roles in development that include vasculogenesis, angiogenesis …
A rich array of prostate cancer molecular biomarkers: opportunities and challenges
I Kohaar, G Petrovics, S Srivastava - International journal of molecular …, 2019 - mdpi.com
Prostate cancer is the most prevalent non-skin cancer in men and is the leading cause of
cancer-related death. Early detection of prostate cancer is largely determined by a widely …
cancer-related death. Early detection of prostate cancer is largely determined by a widely …
Biomarkers of aggressive prostate cancer at diagnosis
BE Boehm, ME York, G Petrovics, I Kohaar… - International Journal of …, 2023 - mdpi.com
In the United States, prostate cancer (CaP) remains the second leading cause of cancer
deaths in men. CaP is predominantly indolent at diagnosis, with a small fraction (25–30%) …
deaths in men. CaP is predominantly indolent at diagnosis, with a small fraction (25–30%) …
PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling
Background PCA3 is a non-coding RNA (ncRNA) that is highly expressed in prostate cancer
(PCa) cells, but its functional role is unknown. To investigate its putative function in PCa …
(PCa) cells, but its functional role is unknown. To investigate its putative function in PCa …
The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of …
E Khosh Kish, M Choudhry, Y Gamallat… - International journal of …, 2022 - mdpi.com
The ETS-related gene (ERG) is proto-oncogene that is classified as a member of the ETS
transcription factor family, which has been found to be consistently overexpressed in about …
transcription factor family, which has been found to be consistently overexpressed in about …
ERG activates the YAP1 transcriptional program and induces the development of age-related prostate tumors
LT Nguyen, MS Tretiakova, MR Silvis, J Lucas… - Cancer cell, 2015 - cell.com
The significance of ERG in human prostate cancer is unclear because mouse prostate is
resistant to ERG-mediated transformation. We determined that ERG activates the …
resistant to ERG-mediated transformation. We determined that ERG activates the …
[HTML][HTML] Racial disparities in prostate cancer: a molecular perspective
A Bhardwaj, SK Srivastava, MA Khan… - Frontiers in …, 2017 - ncbi.nlm.nih.gov
Prostate cancer incidence and mortality rates are remarkably higher in African-American
men as compared to their European-Americans counterparts. Despite these recognitions …
men as compared to their European-Americans counterparts. Despite these recognitions …
Association of ERG and TMPRSS2‐ERG with grade, stage, and prognosis of prostate cancer is dependent on their expression levels
A Font‐Tello, N Juanpere, S De Muga, M Lorenzo… - The …, 2015 - Wiley Online Library
BACKGROUND There is controversy in the literature on the role of the fusion TMPRSS2‐
ERG in the pathogenesis and progression of prostate cancer. The quantitative differences in …
ERG in the pathogenesis and progression of prostate cancer. The quantitative differences in …
Intratumoral T but not B lymphocytes are related to clinical outcome in prostate cancer
A Flammiger, F Bayer, A Cirugeda‐Kühnert, H Huland… - Apmis, 2012 - Wiley Online Library
The number of tumor‐infiltrating lymphocytes is functionally important and correlates with
clinical outcome in several tumor entities. Herein we explore the impact of the density of T …
clinical outcome in several tumor entities. Herein we explore the impact of the density of T …
Genetic and molecular differences in prostate carcinogenesis between African American and Caucasian American men
J Farrell, G Petrovics, DG McLeod… - International journal of …, 2013 - mdpi.com
Prostate cancer is the most common non-skin cancer and the second leading cause of
cancer-related death for men in the United States. Prostate cancer incidence and associated …
cancer-related death for men in the United States. Prostate cancer incidence and associated …