Abstract Background Coronavirus disease 2019 (COVID-19), a contagious infectious
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has …

Deficiency in vitamin D (VitD), a lipid-soluble vitamin and steroid hormone, affects
approximately 24% to 40% of the population of the Western world. In addition to its well …

Background It has been suggested that the baseline triglyceride-glucose (TyG) index, a
simple surrogate measure for insulin resistance, is significantly associated with the …

Cerebral small vessel disease (CSVD) represents a diverse cluster of cerebrovascular
diseases primarily affecting small arteries, capillaries, arterioles and venules. The diagnosis …

Nitric oxide (NO), a small gaseous and multifunctional signaling molecule, is involved in the
maintenance of metabolic and cardiovascular homeostasis. It is endogenously produced in …

Postoperative neurological disorders, including postoperative delirium (POD), postoperative
cognitive dysfunction (POCD), postoperative covert ischemic stroke, and hemorrhagic …

Stroke, the most prevalent cerebrovascular disease, causes serious loss of neurological
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …

Globally, stroke is a leading cause of death and long-term disability. Over the past decades,
several efforts have attempted to discover new drugs or repurpose existing therapeutics to …

An increasing number of studies have focused on the gut microbiota and its relationship with
various neurological diseases. The gut microbiota can affect the metabolic status of the …

Although many studies have addressed the regulatory circuits affecting neuronal activities,
local non-synaptic mechanisms that determine neuronal excitability remain unclear. Here …