Neutrophils produce neutrophil extracellular traps (NETs) by expelling their extracellular
chromatin embedded with citrullinated histone H3, myeloperoxidase, and other intracellular …

Cathelicidins are host defense peptides with antimicrobial and immunomodulatory functions.
These effector molecules of the innate immune system of many vertebrates are diverse in …

Background Multiple inducers of in vitro Neutrophil Extracellular Trap (NET) formation
(NETosis) have been described. Since there is much variation in study design and results …

Under normal conditions, neutrophils are restricted from trafficking into the brain
parenchyma and cerebrospinal fluid by the presence of the brain–blood barrier (BBB). Yet …

Summary Herpes simplex virus (HSV)-1 encephalitis has significant morbidity partly
because of an over-exuberant immune response characterized by leukocyte infiltration into …

Extracellular DNA trap formation is a cellular function of neutrophils, eosinophils, and
basophils that facilitates the immobilization and killing of invading microorganisms in the …

The escalating global prevalence of antimicrobial resistance poses a critical threat,
prompting concerns about its impact on public health. This predicament is exacerbated by …

Neutrophils are crucial mediators of host defense that are recruited to the central nervous
system (CNS) in large numbers during acute bacterial meningitis caused by Streptococcus …

Abstract Background Cystic Fibrosis (CF) is a devastating genetic disease characterised
primarily by unrelenting lung inflammation and infection resulting in premature death and …

In this article, key concepts important for mucosal immunity are discussed. The mucosa is
the largest immune organ of the body. The mucosal barrier-the tight junctions and the “kill …