Enterprise-wide sustainability involves aspects from molecular-scale design to macroscale
facilities. Typically, these aspects are treated as independent sub-problems. Maintaining …

In this work, we first discuss recent advances towards the integration of process design,
process control and process operability from the open literature and then we focus on …

In this paper we present the main foundations and features of an integrated framework and
software platform that enables the use of model-based tools in design, operational …

There is a large variety of methods in literature for process design and control, which can be
classified into two main categories. The methods in the first category have a sequential …

Significant progress in the area of simultaneous design and control for chemical processes
has been achieved and various methodologies have been put forward to address this issue …

We present a framework for the application of design and control optimization via multi‐
parametric programming through four case studies. We develop design dependent multi …

In multi-parametric programming, an optimization problem is solved for a range and as a
function of multiple parameters. In this review, we discuss the main developments of multi …

The design of dynamically operated fixed bed reactors is a challenging task, especially for
highly exothermic reactions. Fluctuations of process conditions such as inlet flow rate and …

We propose a global optimisation approach for the solution of various classes of bilevel
programming problems (BLPP) based on recently developed parametric programming …

The integration of design and control, control and scheduling and design, control and
scheduling, all have been core PSE challenges. While significant progress has been …