Robust, reliable, and quantitative detection of biomarkers at ultra-low concentration is of
great importance in clinical settings. Biosensor, an analytical device used for sensitive and …

Neutrophils, the most abundant type of white blood cells, are pivotal in fighting bacterial
infections due to their immunological and anti-infection capabilities. In recent years …

Single-cell analysis has become increasingly important in uncovering cell heterogeneity,
which has great implications in medicine and biology for a deep understanding of cell …

Tropical diseases present significant challenges to global health, particularly in resource-
limited regions. Early and accurate detection of these diseases is vital for effective …

Rheumatic diseases are a group of highly heterogeneous autoimmune and inflammatory
disorders involving multiple systems. Dysfunction of immune and non-immune cells …

Gouty arthritis (GA) is an immune-mediated disorder characterized by severe inflammation
due to the deposition of monosodium urate (MSU) crystals in the joints. The …

In this review we aim to summarize the current state of methods for label-free identification
and functional characterization of leukocytes with biosensors and novel single cell …

Single-cell imaging, a powerful analytical method to study single-cell behavior, such as
gene expression and protein profiling, provides an essential basis for modern medical …

A single-cell microarray (SCM) influenced by gravitational force is expected to be one of the
simple methods in various fields such as DNA analysis and antibody production. After …

In recent years, miniaturized systems (micro-and nano-devices) called a lab-on-a-chip or
micro-total analysis system (µ-TAS) have received attention as new systems for chemical …