Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …

Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …

Metagenomic assembly enables new organism discovery from microbial communities, but it
can only capture few abundant organisms from most metagenomes. Here we present …

The human gut possesses millions of microbes that define a complex microbial community.
The gut microbiota has been characterized as a vital organ forming its multidirectional …

The composition of the gut microbiome has been associated with clinical responses to
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …

Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is
increasing rapidly with the continuous growth of the economy. A large number of studies …

Biogeography is the study of species distribution and diversity within an ecosystem and is at
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …

Objective The microbiome directly affects the balance of pro-inflammatory and anti-
inflammatory responses in the gut. As microbes thrive on dietary substrates, the question …

Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence
suggesting that the GI tract is involved in this disease. We investigated whether the gut …

The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …