Antioxidative and anti-inflammatory properties of cannabidiol
S Atalay, I Jarocka-Karpowicz, E Skrzydlewska - Antioxidants, 2019 - mdpi.com
Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of
Cannabis sativa L. CBD is non-psychoactive but exerts a number of beneficial …
Cannabis sativa L. CBD is non-psychoactive but exerts a number of beneficial …
Depression in patients with Parkinson's disease: current understanding of its neurobiology and implications for treatment
S Prange, H Klinger, C Laurencin, T Danaila… - Drugs & Aging, 2022 - Springer
Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …
[HTML][HTML] Effects of cannabinoids on sleep and their therapeutic potential for sleep disorders
The recent trend for legalization of medicinal cannabis and cannabinoid-containing
products, together with their soporific effects, has led to a surge of interest of their potential …
products, together with their soporific effects, has led to a surge of interest of their potential …
Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility
CB Klune, B Jin, LA DeNardo - Elife, 2021 - elifesciences.org
The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …
play key roles in memory, cognition, decision making, social behaviors, and mood …
Modulating the neuromodulators: dopamine, serotonin, and the endocannabinoid system
Dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT), and endocannabinoids (ECs) are
key neuromodulators involved in many aspects of motivated behavior, including reward …
key neuromodulators involved in many aspects of motivated behavior, including reward …
Unraveling the time domains of corticosteroid hormone influences on brain activity: rapid, slow, and chronic modes
Brain cells are continuously exposed to corticosteroid hormones, although the levels vary
(eg, after stress). Corticosteroids alter neural activity via two receptor types …
(eg, after stress). Corticosteroids alter neural activity via two receptor types …
A guide to targeting the endocannabinoid system in drug design
A Stasiulewicz, K Znajdek, M Grudzień… - International journal of …, 2020 - mdpi.com
The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …
Antidepressant and anxiolytic effects of medicinal cannabis use in an observational trial
Background: Anxiety and depressive disorders are highly prevalent. Patients are
increasingly using medicinal cannabis products to treat these disorders, but little is known …
increasingly using medicinal cannabis products to treat these disorders, but little is known …
Sigma receptors [σ Rs]: biology in normal and diseased states
CG Rousseaux, SF Greene - Journal of Receptors and Signal …, 2016 - Taylor & Francis
This review compares the biological and physiological function of Sigma receptors [σRs] and
their potential therapeutic roles. Sigma receptors are widespread in the central nervous …
their potential therapeutic roles. Sigma receptors are widespread in the central nervous …
Serotonin receptors in hippocampus
Serotonin is an ancient molecular signal and a recognized neurotransmitter brainwide
distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes …
distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes …