[HTML][HTML] Targeting NaPi2b in ovarian cancer

S Banerjee, R Drapkin, DL Richardson… - Cancer Treatment …, 2023 - Elsevier
Novel biomarkers are needed to direct new treatments for ovarian cancer, a disease for
which the standard of care remains heavily focused on platinum-based chemotherapy …

[HTML][HTML] The role of gut microbiome in cancer genesis and cancer prevention

N Akbar, NA Khan, JS Muhammad, R Siddiqui - Health Sciences Review, 2022 - Elsevier
Cancer is the second leading cause of fatalities at the global level, and the involvement of
microbes in several diseases, including cancer is well known. The gut microbiome is known …

Next generation sequencing and molecular biomarkers in ovarian cancer—an opportunity for targeted therapy

LM Harbin, HH Gallion, DB Allison, JM Kolesar - Diagnostics, 2022 - mdpi.com
Ovarian cancer is the deadliest of all gynecologic malignancies claiming the lives of nearly
14,000 women in the United States annually. Despite therapeutic advances, the ovarian …

Spheroid formation and peritoneal metastasis in ovarian cancer: the role of stromal and immune components

M Rakina, A Kazakova, A Villert, L Kolomiets… - International journal of …, 2022 - mdpi.com
Ovarian cancer (OC) is one of the most common gynecological cancers, with the worst
prognosis and the highest mortality rate. Peritoneal dissemination (or carcinomatosis) …

Sensitivity and specificity of microRNA-204, CA125, and CA19. 9 as biomarkers for diagnosis of ovarian cancer

FT Ali, RM Soliman, NS Hassan, AM Ibrahim… - PLoS …, 2022 - journals.plos.org
Background Ovarian cancer is usually detected at later stages and no effective screening
approach, has been identified. Therefore, sensitive and specific biomarkers for detecting …

Anti-Cancer Activity of Cannabis sativa Phytocannabinoids: Molecular Mechanisms and Potential in the Fight against Ovarian Cancer and Stem Cells

H Koltai, N Shalev - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is the most lethal gynecological malignancy. Cancer stem
cells have been implicated in tumor initiation, progression, and invasion, as well as tumor …

SYNE1 Mutation Is Associated with Increased Tumor Mutation Burden and Immune Cell Infiltration in Ovarian Cancer

LM Harbin, N Lin, FR Ueland, JM Kolesar - International Journal of …, 2023 - mdpi.com
SYNE1, a nuclear envelope protein critical for cellular structure and signaling, is
downregulated in numerous malignancies. SYNE1 alterations are found in 10% of …

Phthalimide‐tethered isatins as novel poly (ADP‐ribose) polymerase inhibitors: Design, synthesis, biological evaluations, and molecular modeling investigations

MA El Hassab, AAA El‐Hafeez, H Almahli… - Archiv der …, 2024 - Wiley Online Library
Humanity is currently facing various diseases with significant mortality rates, particularly
those associated with malignancies. Numerous enzymes and proteins have been identified …

Glucose-6-phosphate dehydrogenase: a therapeutic target for ovarian cancer

C Wang, C Yu, H Chang, J Song, S Zhang… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Ovarian cancer (OC) is a gynecological tumor disease, which is usually
diagnosed at an advanced stage and has a poor prognosis. It has been established that the …

Biomarkers in Ovarian Cancer: Towards Personalized Medicine

C López-Portugués, M Montes-Bayón, P Díez - Proteomes, 2024 - mdpi.com
Ovarian cancer is one of the deadliest cancers in women. The lack of specific symptoms,
especially at the initial stages of disease development, together with the malignancy …