Current perspectives of the signaling pathways directing neural crest induction

TJ Stuhlmiller, MI García-Castro - Cellular and Molecular Life Sciences, 2012 - Springer
The neural crest is a migratory population of embryonic cells with a tremendous potential to
differentiate and contribute to nearly every organ system in the adult body. Over the past two …

Schwann cell-like cells: origin and usability for repair and regeneration of the peripheral and central nervous system

A Hopf, DJ Schaefer, DF Kalbermatten, R Guzman… - Cells, 2020 - mdpi.com
Functional recovery after neurotmesis, a complete transection of the nerve fiber, is often poor
and requires a surgical procedure. Especially for longer gaps (> 3 mm), end-to-end suturing …

Directed differentiation of human pluripotent cells to neural crest stem cells

L Menendez, MJ Kulik, AT Page, SS Park… - Nature protocols, 2013 - nature.com
Multipotent neural crest stem cells (NCSCs) have the potential to generate a wide range of
cell types including melanocytes; peripheral neurons; and smooth muscle, bone, cartilage …

Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells

H Zeng, M Guo, K Martins-Taylor, X Wang, Z Zhang… - PloS one, 2010 - journals.plos.org
Background Directed differentiation of human induced pluripotent stem cells (hiPSC) into
functional, region-specific neural cells is a key step to realizing their therapeutic promise to …

Human neural crest stem cells derived from human ESCs and induced pluripotent stem cells: induction, maintenance, and differentiation into functional schwann cells

Q Liu, SC Spusta, R Mi, RNT Lassiter… - Stem cells …, 2012 - academic.oup.com
The neural crest (NC) is a transient, multipotent, migratory cell population unique to
vertebrates that gives rise to diverse cell lineages. Much of our knowledge of NC …

Isolation and characterization of neural crest stem cells derived from in vitro–differentiated human embryonic stem cells

X Jiang, Y Gwye, SJ McKeown… - Stem cells and …, 2009 - liebertpub.com
The neural crest is a transient structure of vertebrate embryos that initially generates neural
crest stem cells (NCSCs) which then migrate throughout the body to produce a diverse array …

Efficient generation of schwann cells from human embryonic stem cell-derived neurospheres

L Ziegler, S Grigoryan, IH Yang, NV Thakor… - Stem Cell Reviews and …, 2011 - Springer
Schwann cells (SC), the glial cells of peripheral nerves, are involved in many diseases
including Charcot Marie Tooth and neurofibromatosis, and play a pivotal role in peripheral …

Development and in vitro differentiation of Schwann cells

SJ Hörner, N Couturier, DC Gueiber, M Hafner… - Cells, 2022 - mdpi.com
Schwann cells are glial cells of the peripheral nervous system. They exist in several
subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are …

Mesenchymal stem cells increase hippocampal neurogenesis and counteract depressive-like behavior

M Tfilin, E Sudai, A Merenlender, I Gispan… - Molecular …, 2010 - nature.com
Adult bone marrow-derived mesenchymal stem cells (MSCs) are regarded as potential
candidates for treatment of neurodegenerative disorders, because of their ability to promote …

[HTML][HTML] Neural crest stem cells and their potential therapeutic applications

JA Liu, M Cheung - Developmental biology, 2016 - Elsevier
The neural crest (NC) is a remarkable transient structure generated during early vertebrate
development. The neural crest progenitors have extensive migratory capacity and …