Bionanoparticles in cancer imaging, diagnosis, and treatment

Y Li, Q Bao, S Yang, M Yang, C Mao - View, 2022 - Wiley Online Library
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

Graphene oxide–DNA based sensors

L Gao, C Lian, Y Zhou, L Yan, Q Li, C Zhang… - Biosensors and …, 2014 - Elsevier
Since graphene oxide (GO) is readily available and exhibits exceptional optical, electrical,
mechanical and chemical properties, it has attracted increasing interests for use in GO–DNA …

Thioflavin T as a fluorescence probe for biosensing applications

FY Khusbu, X Zhou, H Chen, C Ma, K Wang - TrAC Trends in Analytical …, 2018 - Elsevier
Thioflavin T (ThT), a water-soluble fluorescence probe and the conventional dye for the
detection of amyloid fibrils has recently been demonstrated to recognize and bind nucleic …

Antibody-powered nucleic acid release using a DNA-based nanomachine

S Ranallo, C Prévost-Tremblay, A Idili… - Nature …, 2017 - nature.com
A wide range of molecular devices with nanoscale dimensions have been recently designed
to perform a variety of functions in response to specific molecular inputs. Only limited …

Programmable DNA switches and their applications

SG Harroun, C Prévost-Tremblay, D Lauzon… - Nanoscale, 2018 - pubs.rsc.org
DNA switches are ideally suited for numerous nanotechnological applications, and
increasing efforts are being directed toward their engineering. In this review, we discuss how …

DNA-based scaffolds for sensing applications

S Ranallo, A Porchetta, F Ricci - Analytical chemistry, 2018 - ACS Publications
DNA nanotechnology employs synthetic nucleic acid strands to design and engineer
nanoscale structural and functional systems of increasing complexity that may find …

A modular, DNA‐based beacon for single‐step fluorescence detection of antibodies and other proteins

S Ranallo, M Rossetti, KW Plaxco… - Angewandte Chemie …, 2015 - Wiley Online Library
A versatile platform for the one‐step fluorescence detection of both monovalent and
multivalent proteins has been developed. This system is based on a conformation‐switching …

Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe

L Lu, DSH Chan, DWJ Kwong, HZ He, CH Leung… - Chemical …, 2014 - pubs.rsc.org
A series of luminescent Ir (III) complexes were synthesised and evaluated for their ability to
act as G-quadruplex-selective probes. A novel Ir (III) complex was found to be highly …

A CRISPR-derived biosensor for the sensitive detection of transcription factors based on the target-induced inhibition of Cas12a activation

B Li, A Xia, S Zhang, T Suo, Y Ma, H Huang… - Biosensors and …, 2021 - Elsevier
Transcription factors (TFs) are the key proteins for the decision of cell fates, and they have
been recognized as potent markers for diagnostic and treatment of diseases. Herein, we …

Allosterically tunable, DNA-based switches triggered by heavy metals

A Porchetta, A Vallée-Bélisle, KW Plaxco… - Journal of the American …, 2013 - ACS Publications
Here we demonstrate the rational design of allosterically controllable, metal-ion-triggered
molecular switches. Specifically, we designed DNA sequences that adopt two low energy …