Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

Pharmacogenomics (PGx) relates to the study of genetic factors determining variability in
drug response. Implementing PGx testing in paediatric patients can enhance drug safety …

Background Variability in drug efficacy and adverse effects are observed in clinical practice.
While the extent of genetic variability in classic pharmacokinetic genes is rather well …

Pharmacogenomics (PGx) investigates the influence of genetics on drug responses,
enabling tailored treatments for personalized healthcare. This study assessed the accuracy …

Background Analytical validity is a prerequisite to use a next generation sequencing (NGS)-
based application as an in vitro diagnostic test or a companion diagnostic in clinical practice …

Leishmaniasis is an infectious disease caused by protozoan parasites from different species
of leishmania. The disease is transmitted by female sandflies that carry these parasites. In …

One of the significant health issues that plague people all over the world is immunological
dysfunction, which includes allergies. Allergens include things like pollen, dust mites, food …

The importance of sphingolipids and phosphoinositides in cellular functions is highlighted,
given the intricate nature of the lipidome and the critical role of membrane proteins. There …

This study analyzed clinically actionable pharmacogenotypes for clopidogrel, warfarin,
statins, thiopurines, and tacrolimus using microarray data for 2121 participants (55–85 …

Abstract Implementing Personalized Medicine in the operational and functional context of a
healthcare system is a complex challenge for most countries. Pharmacogenetics represents …