HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

Abstract Purpose of Review This review will outline the multilevel effects of biological sex on
HIV acquisition, pathogenesis, treatment response, and prospects for cure. Potential …

In light of the increasing global burden of new HIV infections, growing financial
requirements, and shifting funding landscape, the global health community must accelerate …

The impact of the microbiome on HIV disease is widely acknowledged although the
mechanisms downstream of fluctuations in microbial composition remain speculative. We …

Background Chronic inflammation and residual HIV transcription persist in people living with
HIV (PLWH) receiving antiretroviral therapy (ART), thus increasing the risk of developing …

Chronic inflammation and immune dysfunction play a key role in the development of non-
AIDS–related comorbidities. The aim of our study was to characterize the functional …

Despite the success of antiretroviral therapy (ART), people living with HIV continue to suffer
from high burdens of respiratory infections, lung cancers and chronic lung disease at a …

Combination antiretroviral therapy (ART) to treat human immunodeficiency virus (HIV)
infection has proven remarkably successful–for those who can access and afford it–yet HIV …

Summary Background A low CD4/CD8 ratio during antiretroviral therapy (ART) identifies
people with heightened immunosenescence and increased risk of mortality. We aimed to …

The increased prevalence of age-related comorbidities and mortality is worrisome in ageing
HIV-infected patients. Here, we aim to analyse the different ageing mechanisms with regard …